The first versatile human iPSC-based model of ectopic virus induction allows new insights in RNA-virus disease

A detailed description of pathophysiological effects that viruses exert on their host is still challenging. For the first time, we report a highly controllable viral expression model based on an iPS-cell line from a healthy human donor. The established viral model system enables a dose-dependent and...

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Detalles Bibliográficos
Autores principales: Peischard, Stefan, Ho, Huyen Tran, Piccini, Ilaria, Strutz-Seebohm, Nathalie, Röpke, Albrecht, Liashkovich, Ivan, Gosain, Hiteshika, Rieger, Bettina, Klingel, Karin, Eggers, Britta, Marcus, Katrin, Linke, Wolfgang A., Müller, Frank Ulrich, Ludwig, Stephan, Greber, Boris, Busch, Karin, Seebohm, Guiscard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546621/
https://www.ncbi.nlm.nih.gov/pubmed/33033381
http://dx.doi.org/10.1038/s41598-020-72966-9

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