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Suppression of inflammatory arthritis in human serum paraoxonase 1 transgenic mice
Paraoxonase 1(PON1) is an HDL-associated protein, which metabolizes inflammatory, oxidized lipids associated with atherosclerotic plaque development. Because oxidized lipid mediators have also been implicated in the pathogenesis of rheumatoid arthritis (RA), we evaluated the role of PON1 in murine i...
Autores principales: | Charles-Schoeman, Christina, Wang, Jennifer, Shahbazian, Ani, Lee, Yuen Yin, Wang, Xiaoyan, Grijalva, Victor, Brahn, Ernest, Shih, Diana M., Devarajan, Asokan, Montano, Christy, Lusis, Aldons J., Reddy, Srinivasa T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546628/ https://www.ncbi.nlm.nih.gov/pubmed/33033318 http://dx.doi.org/10.1038/s41598-020-74016-w |
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