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Generation of an immortalised erythroid cell line from haematopoietic stem cells of a haemoglobin E/β-thalassemia patient

The β-thalassemia syndromes are the most prevalent genetic disorder globally, characterised by reduced or absent β-globin chain synthesis. HbE/β-thalassemia is a subtype of β-thalassemia with extremely high frequency in Asia. Studying molecular defects behind β-thalassemia is severely impeded by pau...

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Detalles Bibliográficos
Autores principales:	Trakarnsanga, Kongtana, Tipgomut, Chartsiam, Metheetrairut, Chanatip, Wattanapanitch, Methichit, Khuhapinant, Archrob, Poldee, Saiphon, Kurita, Ryo, Nakamura, Yukio, Srisawat, Chatchawan, Frayne, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546635/ https://www.ncbi.nlm.nih.gov/pubmed/33033327 http://dx.doi.org/10.1038/s41598-020-73991-4

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