Proof of SARS-CoV-2 genomes in endomyocardial biopsy with latency after acute infection

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has reached pandemic levels. Cardiovascular complications in COVID-19 have been reported frequently, however evidence for a causal relationship has not been esta...

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Detalles Bibliográficos
Autores principales: Pietsch, Heiko, Escher, Felicitas, Aleshcheva, Ganna, Baumeier, Christian, Morawietz, Lars, Elsaesser, Albrecht, Schultheiss, Heinz-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546659/
https://www.ncbi.nlm.nih.gov/pubmed/33045427
http://dx.doi.org/10.1016/j.ijid.2020.10.012
Descripción
Sumario:The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has reached pandemic levels. Cardiovascular complications in COVID-19 have been reported frequently, however evidence for a causal relationship has not been established. This report describes the detection of SARS-CoV-2 viral genomes in a patient with symptoms of heart failure, in whom endomyocardial biopsy was investigated following a latency period of 4 weeks after the onset of pulmonary symptoms. The viral infection was accompanied by myocardial inflammation indicating an infection of the heart muscle.

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