Bilateral macular hemorrhage in a patient with COVID-19

PURPOSE: We report a case of a patient with a known hereditary spherocytosis who developed a bilateral macular hemorrhage in concurrence with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related respiratory syndrome. OBSERVATIONS: Blood tests showed severe hemolytic anemia. Interesti...

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Detalles Bibliográficos
Autores principales: D'Aloisio, Rossella, Nasillo, Vincenzo, Gironi, Matteo, Mastropasqua, Rodolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546668/
https://www.ncbi.nlm.nih.gov/pubmed/33073058
http://dx.doi.org/10.1016/j.ajoc.2020.100958
Descripción
Sumario:PURPOSE: We report a case of a patient with a known hereditary spherocytosis who developed a bilateral macular hemorrhage in concurrence with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related respiratory syndrome. OBSERVATIONS: Blood tests showed severe hemolytic anemia. Interestingly, the peripheral blood smear demonstrated a mixed pathogenesis of the hemolytic process (cold-agglutinin-mediated and non-immune-mediated due to spherocytosis). CONCLUSIONS AND IMPORTANCE: We argue that SARS-CoV-2 could have triggered the hemolytic process, which led to retinal hemorrhages due to endothelial anoxia from the low oxygen carrying capacity.

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