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Topoisomerase II alpha promotes gallbladder cancer proliferation and metastasis through activating phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway

BACKGROUND: : Topoisomerase II alpha (TOP2A) has been reported to play a crucial role in the tumorigenesis of various cancer types. However, the biological role of TOP2A in gallbladder cancer (GBC) remains unknown. The current study aimed to explore the function and potential mechanism of TOP2A in G...

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Detalles Bibliográficos
Autores principales:	Lyu, Wen-Jie, Shu, Yi-Jun, Liu, Ying-Bin, Dong, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546881/ https://www.ncbi.nlm.nih.gov/pubmed/32925281 http://dx.doi.org/10.1097/CM9.0000000000001075

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