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Multidimensional analyses reveal modulation of adaptive and innate immune subsets by tuberculosis vaccines
We characterize the breadth, function and phenotype of innate and adaptive cellular responses in a prevention of Mycobacterium tuberculosis infection trial. Responses are measured by whole blood intracellular cytokine staining at baseline and 70 days after vaccination with H4:IC31 (subunit vaccine c...
Autores principales: | Rozot, Virginie, Nemes, Elisa, Geldenhuys, Hennie, Musvosvi, Munyaradzi, Toefy, Asma, Rantangee, Frances, Makhethe, Lebohang, Erasmus, Mzwandile, Bilek, Nicole, Mabwe, Simbarashe, Finak, Greg, Fulp, William, Ginsberg, Ann M., Hokey, David A., Shey, Muki, Gurunathan, Sanjay, DiazGranados, Carlos, Bekker, Linda-Gail, Hatherill, Mark, Scriba, Thomas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547090/ https://www.ncbi.nlm.nih.gov/pubmed/33037320 http://dx.doi.org/10.1038/s42003-020-01288-3 |
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