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Dexamethasone-Loaded Thermosensitive Hydrogel Suppresses Inflammation and Pain in Collagen-Induced Arthritis Rats
PURPOSE: To overcome negative adverse effects and improve therapeutic index of dexamethasone (Dex) in rheumatoid arthritis (RA), we developed a novel sustained release formulation-intra-articular injectable dexamethasone-loaded thermosensitive hydrogel (DLTH) with chitosan-glycerin-borax as carrier...
Autores principales: | Wang, Qi-Shan, Xu, Bing-Xin, Fan, Kai-Jian, Li, Yun-Wu, Wu, Jing, Wang, Ting-Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547127/ https://www.ncbi.nlm.nih.gov/pubmed/33116399 http://dx.doi.org/10.2147/DDDT.S256850 |
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