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Aβ oligomer induced cognitive impairment and evaluation of ACU193‐MNS‐based MRI in rabbit

INTRODUCTION: Amyloid‐beta oligomers (AβOs) accumulate in Alzheimer's disease and may instigate neuronal pathology and cognitive impairment. We examined the ability of a new probe for molecular magnetic resonance imaging (MRI) to detect AβOs in vivo, and we tested the behavioral impact of AβOs...

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Detalles Bibliográficos
Autores principales: Rozema, Nicholas B., Procissi, Daniele, Bertolino, Nicola, Viola, Kirsten L., Nandwana, Vikas, Abdul, Nafay, Pribus, Sophia, Dravid, Vinayak, Klein, William L., Disterhoft, John F., Weiss, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547311/
https://www.ncbi.nlm.nih.gov/pubmed/33072847
http://dx.doi.org/10.1002/trc2.12087