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Does conserved domain SOD1 mutation has any role in ALS severity and therapeutic outcome?
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative fatal disease that can affect the neurons of brain and spinal cord. ALS genetics has identified various genes to be associated with disease pathology. Oxidative stress induced bunina and lewy bodies formation can be r...
Autores principales: | Pal, Surinder, Tiwari, Abha, Sharma, Kaushal, Sharma, Suresh Kumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547430/ https://www.ncbi.nlm.nih.gov/pubmed/33036560 http://dx.doi.org/10.1186/s12868-020-00591-3 |
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