Cerebral Herniation Secondary to Stroke-Associated Hemorrhagic Transformation, Fulminant Cerebral Edema in Setting of COVID-19 Associated ARDS and Active Malignancy

SARS-CoV-2 infection has been associated with ischemic stroke as well as systemic complications such as acute respiratory failure; cytotoxic edema is a well-known sequelae of acute ischemic stroke and can be worsened by the presence of hypercarbia induced by respiratory failure. We present the case...

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Autores principales: Dakay, Katarina, Kaur, Gurmeen, Mayer, Stephan A., Santarelli, Justin, Gandhi, Chirag, Al-Mufti, Fawaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547646/
https://www.ncbi.nlm.nih.gov/pubmed/33096499
http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2020.105397
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author Dakay, Katarina
Kaur, Gurmeen
Mayer, Stephan A.
Santarelli, Justin
Gandhi, Chirag
Al-Mufti, Fawaz
author_facet Dakay, Katarina
Kaur, Gurmeen
Mayer, Stephan A.
Santarelli, Justin
Gandhi, Chirag
Al-Mufti, Fawaz
author_sort Dakay, Katarina
collection PubMed
description SARS-CoV-2 infection has been associated with ischemic stroke as well as systemic complications such as acute respiratory failure; cytotoxic edema is a well-known sequelae of acute ischemic stroke and can be worsened by the presence of hypercarbia induced by respiratory failure. We present the case of a very rapid neurologic and radiographic decline of a patient with an acute ischemic stroke who developed rapid fulminant cerebral edema leading to herniation in the setting of hypercarbic respiratory failure attributed to SARS-CoV-2 infection. Given the elevated incidence of cerebrovascular complications in patients with COVID-19, it is imperative for clinicians to be aware of the risk of rapidly progressive cerebral edema in patients who develop COVID-19 associated acute respiratory distress syndrome.
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spelling pubmed-75476462020-10-13 Cerebral Herniation Secondary to Stroke-Associated Hemorrhagic Transformation, Fulminant Cerebral Edema in Setting of COVID-19 Associated ARDS and Active Malignancy Dakay, Katarina Kaur, Gurmeen Mayer, Stephan A. Santarelli, Justin Gandhi, Chirag Al-Mufti, Fawaz J Stroke Cerebrovasc Dis Case Report SARS-CoV-2 infection has been associated with ischemic stroke as well as systemic complications such as acute respiratory failure; cytotoxic edema is a well-known sequelae of acute ischemic stroke and can be worsened by the presence of hypercarbia induced by respiratory failure. We present the case of a very rapid neurologic and radiographic decline of a patient with an acute ischemic stroke who developed rapid fulminant cerebral edema leading to herniation in the setting of hypercarbic respiratory failure attributed to SARS-CoV-2 infection. Given the elevated incidence of cerebrovascular complications in patients with COVID-19, it is imperative for clinicians to be aware of the risk of rapidly progressive cerebral edema in patients who develop COVID-19 associated acute respiratory distress syndrome. Elsevier Inc. 2020-12 2020-10-10 /pmc/articles/PMC7547646/ /pubmed/33096499 http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2020.105397 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Case Report
Dakay, Katarina
Kaur, Gurmeen
Mayer, Stephan A.
Santarelli, Justin
Gandhi, Chirag
Al-Mufti, Fawaz
Cerebral Herniation Secondary to Stroke-Associated Hemorrhagic Transformation, Fulminant Cerebral Edema in Setting of COVID-19 Associated ARDS and Active Malignancy
title Cerebral Herniation Secondary to Stroke-Associated Hemorrhagic Transformation, Fulminant Cerebral Edema in Setting of COVID-19 Associated ARDS and Active Malignancy
title_full Cerebral Herniation Secondary to Stroke-Associated Hemorrhagic Transformation, Fulminant Cerebral Edema in Setting of COVID-19 Associated ARDS and Active Malignancy
title_fullStr Cerebral Herniation Secondary to Stroke-Associated Hemorrhagic Transformation, Fulminant Cerebral Edema in Setting of COVID-19 Associated ARDS and Active Malignancy
title_full_unstemmed Cerebral Herniation Secondary to Stroke-Associated Hemorrhagic Transformation, Fulminant Cerebral Edema in Setting of COVID-19 Associated ARDS and Active Malignancy
title_short Cerebral Herniation Secondary to Stroke-Associated Hemorrhagic Transformation, Fulminant Cerebral Edema in Setting of COVID-19 Associated ARDS and Active Malignancy
title_sort cerebral herniation secondary to stroke-associated hemorrhagic transformation, fulminant cerebral edema in setting of covid-19 associated ards and active malignancy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547646/
https://www.ncbi.nlm.nih.gov/pubmed/33096499
http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2020.105397
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