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N(6)-methyladenosine-dependent pri-miR-17-92 maturation suppresses PTEN/TMEM127 and promotes sensitivity to everolimus in gastric cancer
N(6)-methyladenosine (m(6)A) is the most common epigenetic RNA modification with essential roles in cancer progression. However, roles of m(6)A and its regulator METTL3 on non-coding RNA in gastric cancer are unknown. In this study, we found elevated levels of m(6)A and METTL3 in gastric cancer. Inc...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547657/ https://www.ncbi.nlm.nih.gov/pubmed/33037176 http://dx.doi.org/10.1038/s41419-020-03049-w |