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Structural insights into assembly of the ribosomal nascent polypeptide exit tunnel
The nascent polypeptide exit tunnel (NPET) is a major functional center of 60S ribosomal subunits. However, little is known about how the NPET is constructed during ribosome assembly. We utilized molecular genetics, biochemistry, and cryo-electron microscopy (cryo-EM) to investigate the functions of...
Autores principales: | Wilson, Daniel M., Li, Yu, LaPeruta, Amber, Gamalinda, Michael, Gao, Ning, Woolford, John L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547690/ https://www.ncbi.nlm.nih.gov/pubmed/33037216 http://dx.doi.org/10.1038/s41467-020-18878-8 |
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