Cargando…

Two genetic variants explain the association of European ancestry with multiple sclerosis risk in African-Americans

Epidemiological studies have suggested differences in the rate of multiple sclerosis (MS) in individuals of European ancestry compared to African ancestry, motivating genetic scans to identify variants that could contribute to such patterns. In a whole-genome scan in 899 African-American cases and 1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nakatsuka, Nathan, Patterson, Nick, Patsopoulos, Nikolaos A., Altemose, Nicolas, Tandon, Arti, Beecham, Ashley H., McCauley, Jacob L., Isobe, Noriko, Hauser, Stephen, De Jager, Philip L., Hafler, David A., Oksenberg, Jorge R., Reich, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547691/ https://www.ncbi.nlm.nih.gov/pubmed/33037294 http://dx.doi.org/10.1038/s41598-020-74035-7

Ejemplares similares

Single-Nucleotide Polymorphisms in LPA Explain Most of the Ancestry-Specific Variation in Lp(a) Levels in African Americans
por: Deo, Rahul C., et al.
Publicado: (2011)

Sensitive Detection of Chromosomal Segments of Distinct Ancestry in Admixed Populations
por: Price, Alkes L., et al.
Publicado: (2009)

Native ancestry is associated with optic neuritis and age of onset in hispanics with multiple sclerosis
por: Amezcua, Lilyana, et al.
Publicado: (2018)

African Ancestry and Its Correlation to Type 2 Diabetes in African Americans: A Genetic Admixture Analysis in Three U.S. Population Cohorts
por: Cheng, Ching-Yu, et al.
Publicado: (2012)

Correction: African Ancestry and Its Correlation to Type 2 Diabetes in African Americans: A Genetic Admixture Analysis in Three U.S. Population Cohorts
por: Cheng, Ching-Yu, et al.
Publicado: (2012)

Effects of cis and trans Genetic Ancestry on Gene Expression in African Americans
por: Price, Alkes L., et al.
Publicado: (2008)

Ancestral risk modification for multiple sclerosis susceptibility detected across the Major Histocompatibility Complex in a multi-ethnic population
por: Beecham, Ashley H., et al.
Publicado: (2022)

The landscape of Neandertal ancestry in present-day humans
por: Sankararaman, Sriram, et al.
Publicado: (2014)

Phenotypic variance explained by local ancestry in admixed African Americans
por: Shriner, Daniel, et al.
Publicado: (2015)

A knowledge-driven interaction analysis reveals potential neurodegenerative mechanism of multiple sclerosis susceptibility
por: Bush, William S., et al.
Publicado: (2011)

Does Genetic Ancestry Explain Higher Values of Glycated Hemoglobin in African Americans?
por: Maruthur, Nisa M., et al.
Publicado: (2011)

Fine-Mapping Array Design for Multi-Ethnic Studies of Multiple Sclerosis
por: Beecham, Ashley H., et al.
Publicado: (2019)

Aberrant STAT phosphorylation signaling in peripheral blood mononuclear cells from multiple sclerosis patients
por: Canto, Ester, et al.
Publicado: (2018)

MS in self-identified Hispanic/Latino individuals living in the US
por: Amezcua, Lilyana, et al.
Publicado: (2017)

The Genetic Ancestry of African Americans, Latinos, and European Americans across the United States
por: Bryc, Katarzyna, et al.
Publicado: (2015)

Amerind Ancestry, Socioeconomic Status and the Genetics of Type 2 Diabetes in a Colombian Population
por: Campbell, Desmond D., et al.
Publicado: (2012)

Genetic Differences between the Determinants of Lipid Profile Phenotypes in African and European Americans: The Jackson Heart Study
por: Deo, Rahul C., et al.
Publicado: (2009)

A High-Density Admixture Scan in 1,670 African Americans with Hypertension
por: Deo, Rahul C, et al.
Publicado: (2007)

Challenging the Role of Genetic Ancestry in Explaining Racial/Ethnic Health Disparities
por: Non, Amy L., et al.
Publicado: (2021)

Discerning the Ancestry of European Americans in Genetic Association Studies
por: Price, Alkes L, et al.
Publicado: (2008)

ContamLD: estimation of ancient nuclear DNA contamination using breakdown of linkage disequilibrium
por: Nakatsuka, Nathan, et al.
Publicado: (2020)

Fine-Mapping the Genetic Association of the Major Histocompatibility Complex in Multiple Sclerosis: HLA and Non-HLA Effects
por: Patsopoulos, Nikolaos A., et al.
Publicado: (2013)

A Major Histocompatibility Class I Locus Contributes to Multiple Sclerosis Susceptibility Independently from HLA-DRB1*15:01
por: Cree, Bruce A. C., et al.
Publicado: (2010)

Enterolignan Production in a Flaxseed Intervention Study in Postmenopausal US Women of African Ancestry and European Ancestry
por: McCann, Susan E., et al.
Publicado: (2021)

Characterizing the admixed African ancestry of African Americans
por: Zakharia, Fouad, et al.
Publicado: (2009)

Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci
por: McCauley, Jacob L., et al.
Publicado: (2010)

Admixture Mapping Scans Identify a Locus Affecting Retinal Vascular Caliber in Hypertensive African Americans: the Atherosclerosis Risk in Communities (ARIC) Study
por: Cheng, Ching-Yu, et al.
Publicado: (2010)

Missing in Action: African Ancestry Brain Research
por: Weinberger, Daniel R., et al.
Publicado: (2020)

A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis
por: Ban, Maria, et al.
Publicado: (2010)

Peptide ancestry informative markers in uterine neoplasms from women of European, African, and Asian ancestry
por: Bateman, Nicholas W., et al.
Publicado: (2021)

A Genome-wide Admixture Scan for Ancestry-linked Genes Predisposing to Sarcoidosis in African Americans
por: Rybicki, Benjamin A., et al.
Publicado: (2010)

Explaining the visible and the invisible: Public knowledge of genetics, ancestry, physical appearance and race in Colombia
por: Schwartz-Marín, Ernesto, et al.
Publicado: (2015)

A pragmatic view on pragmatic trials
por: Patsopoulos, Nikolaos A.
Publicado: (2011)

African ancestry, lung function and the effect of genetics
por: Menezes, Ana Maria B., et al.
Publicado: (2015)

Ancestry-associated transcriptomic profiles of breast cancer in patients of African, Arab, and European ancestry
por: Roelands, Jessica, et al.
Publicado: (2021)

PRState: Incorporating genetic ancestry in prostate cancer risk scores for men of African ancestry
por: Pagadala, Meghana S., et al.
Publicado: (2022)

Extensive set of African ancestry-informative markers (AIMs) to study ancestry and population health
por: Boudeau, Samantha, et al.
Publicado: (2023)

Genetic and Genomic Epidemiology of Stroke in People of African Ancestry
por: Prapiadou, Savvina, et al.
Publicado: (2021)

Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics
por: Chan, Tsz Fung, et al.
Publicado: (2023)

Evaluating the promise of inclusion of African ancestry populations in genomics
por: Bentley, Amy R., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_l17uaqdm5us28gbi03sg8q66cb