Cargando…

Glutamine-to-glutamate ratio in the nucleus accumbens predicts effort-based motivated performance in humans

Substantial evidence implicates the nucleus accumbens in motivated performance, but very little is known about the neurochemical underpinnings of individual differences in motivation. Here, we applied (1)H magnetic resonance spectroscopy ((1)H-MRS) at ultra-high-field in the nucleus accumbens and in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Strasser, Alina, Luksys, Gediminas, Xin, Lijing, Pessiglione, Mathias, Gruetter, Rolf, Sandi, Carmen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547698/ https://www.ncbi.nlm.nih.gov/pubmed/32688366 http://dx.doi.org/10.1038/s41386-020-0760-6

Ejemplares similares

Glutathione in the nucleus accumbens regulates motivation to exert reward-incentivized effort
por: Zalachoras, Ioannis, et al.
Publicado: (2022)

Metabolic signature in nucleus accumbens for anti-depressant-like effects of acetyl-L-carnitine
por: Cherix, Antoine, et al.
Publicado: (2020)

Neural Mechanisms Underlying Motivation of Mental Versus Physical Effort
por: Schmidt, Liane, et al.
Publicado: (2012)

Regulation of glutamate homeostasis in the nucleus accumbens by astrocytic CB1 receptors and its role in cocaine-motivated behaviors
por: Zhang, Lan-Yuan, et al.
Publicado: (2022)

Thalamo-Nucleus Accumbens Projections in Motivated Behaviors and Addiction
por: De Groote, Aurélie, et al.
Publicado: (2021)

Detailed classification of swimming paths in the Morris Water Maze: multiple strategies within one trial
por: Gehring, Tiago V., et al.
Publicado: (2015)

Desire and Dread from the Nucleus Accumbens: Cortical Glutamate and Subcortical GABA Differentially Generate Motivation and Hedonic Impact in the Rat
por: Faure, Alexis, et al.
Publicado: (2010)

Nucleus Accumbens Mediates Relative Motivation for Rewards in the Absence of Choice
por: Clithero, John A., et al.
Publicado: (2011)

Nucleus Accumbens Fast-spiking Interneurons in Motivational and Addictive Behaviors
por: Schall, Terra A., et al.
Publicado: (2020)

Chronic inflammatory pain decreases the glutamate vesicles in presynaptic terminals of the nucleus accumbens
por: Qi, Chuchu, et al.
Publicado: (2018)

Glutamate delta-1 receptor regulates cocaine-induced plasticity in the nucleus accumbens
por: Liu, Jinxu, et al.
Publicado: (2018)

Cocaine-induced sensitization and glutamate plasticity in the nucleus accumbens core: effects of sex
por: Catalfio, Amanda M., et al.
Publicado: (2023)

Sex differences in pre- and post-synaptic glutamate signaling in the nucleus accumbens core
por: Knouse, Melissa C., et al.
Publicado: (2023)

Context coding in the mouse nucleus accumbens modulates motivationally relevant information
por: Gmaz, Jimmie M., et al.
Publicado: (2022)

Oxygen responses within the nucleus accumbens are associated with individual differences in effort exertion in rats
por: Hailwood, Jonathan M., et al.
Publicado: (2018)

Differential effects of natural rewards and pain on vesicular glutamate transporter expression in the nucleus accumbens
por: Tukey, David S, et al.
Publicado: (2013)

Metabotropic Glutamate Receptors 7 within the Nucleus Accumbens are Involved in Relief Learning in Rats
por: Kahl, Evelyn, et al.
Publicado: (2016)

Effect of Aggressive Experience in Female Syrian Hamsters on Glutamate Receptor Expression in the Nucleus Accumbens
por: Borland, Johnathan M., et al.
Publicado: (2020)

Nucleus Accumbens Microcircuit Underlying D2-MSN-Driven Increase in Motivation
por: Soares-Cunha, Carina, et al.
Publicado: (2018)

Hypersensitivity to amphetamine's psychomotor and reinforcing effects in serotonin transporter knockout rats: Glutamate in the nucleus accumbens
por: Caffino, Lucia, et al.
Publicado: (2020)

Trait anxiety on effort allocation to monetary incentives: a behavioral and high-density EEG study
por: Berchio, Cristina, et al.
Publicado: (2019)

Repeated cycles of chronic intermittent ethanol exposure increases basal glutamate in the nucleus accumbens of mice without affecting glutamate transport
por: Griffin, William C., et al.
Publicado: (2015)

Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation
por: Soares-Cunha, Carina, et al.
Publicado: (2016)

Altered gating of K(v)1.4 in the nucleus accumbens suppresses motivation for reward
por: O'Donovan, Bernadette, et al.
Publicado: (2019)

Glutamate and Opioid Antagonists Modulate Dopamine Levels Evoked by Innately Attractive Male Chemosignals in the Nucleus Accumbens of Female Rats
por: Sánchez-Catalán, María-José, et al.
Publicado: (2017)

Brain-Wide Mapping of Afferent Inputs to Accumbens Nucleus Core Subdomains and Accumbens Nucleus Subnuclei
por: Ma, Liping, et al.
Publicado: (2020)

Quantifying absolute glutamate concentrations in nucleus accumbens of prescription opioid addicts by using (1)H MRS
por: Liu, Xi‐Long, et al.
Publicado: (2017)

Glutamate Afferents From the Medial Prefrontal Cortex Mediate Nucleus Accumbens Activation by Female Sexual Behavior
por: Moore, Kelsey M., et al.
Publicado: (2019)

Nucleus accumbens core acetylcholine receptors modulate the balance of flexible and inflexible cue-directed motivation
por: Townsend, Erica S., et al.
Publicado: (2023)

Adolescent Mice Are Resilient to Alcohol Withdrawal-Induced Anxiety and Changes in Indices of Glutamate Function within the Nucleus Accumbens
por: Lee, Kaziya M., et al.
Publicado: (2016)

Impairment of glutamate homeostasis in the nucleus accumbens core underpins cross-sensitization to cocaine following chronic restraint stress
por: Avalos, María P., et al.
Publicado: (2022)

Peripubertal stress increases play fighting at adolescence and modulates nucleus accumbens CB1 receptor expression and mitochondrial function in the amygdala
por: Papilloud, Aurélie, et al.
Publicado: (2018)

Encoding of Aversion by Dopamine and the Nucleus Accumbens
por: McCutcheon, James E., et al.
Publicado: (2012)

Nucleus Accumbens Modulation in Reward and Aversion
por: Klawonn, Anna M., et al.
Publicado: (2019)

The Role of Neuropeptide Y in the Nucleus Accumbens
por: Tanaka, Masaki, et al.
Publicado: (2021)

A computational account of why more valuable goals seem to require more effortful actions
por: Bioud, Emmanuelle, et al.
Publicado: (2022)

White-matter tract connecting anterior insula to nucleus accumbens predicts greater future motivation in adolescents
por: Leong, Josiah K., et al.
Publicado: (2020)

Amyloid-β oligomers in the Nucleus Accumbens Decrease Motivation via Insertion of Calcium-Permeable AMPA Receptors
por: Guo, Changyong, et al.
Publicado: (2022)

Place preference induced by nucleus accumbens amphetamine is impaired by local blockade of Group II metabotropic glutamate receptors in rats
por: Gerdjikov, Todor V, et al.
Publicado: (2006)

A Rat Model of Cocaine-Alcohol Polysubstance Use Reveals Altered Cocaine Seeking and Glutamate Levels in the Nucleus Accumbens
por: Stennett, Bethany A., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_k65rf1c88jnbjno42lrf05k0r9