Cargando…

Lupus Vulgaris and Lichen Scrofulosorum with Disseminated Tuberculosis

Cutaneous tuberculosis (CTB) represents only 1%–2% of extrapulmonary forms of tuberculosis (TB). CTB can present in the isolation or coexist with pulmonary and disseminated forms of TB. Pathologically confirmed lupus vulgaris (LV) coexisting with lichen scrofulosorum with disseminated TB is presente...

Descripción completa

Detalles Bibliográficos
Autores principales: Okoh, Nnenna Uzunma, Nnaji, T., Onyekonwu, Chinwe L., Emeka, Chika Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547755/
https://www.ncbi.nlm.nih.gov/pubmed/33100470
http://dx.doi.org/10.4103/nmj.NMJ_135_19
_version_ 1783592486424281088
author Okoh, Nnenna Uzunma
Nnaji, T.
Onyekonwu, Chinwe L.
Emeka, Chika Mary
author_facet Okoh, Nnenna Uzunma
Nnaji, T.
Onyekonwu, Chinwe L.
Emeka, Chika Mary
author_sort Okoh, Nnenna Uzunma
collection PubMed
description Cutaneous tuberculosis (CTB) represents only 1%–2% of extrapulmonary forms of tuberculosis (TB). CTB can present in the isolation or coexist with pulmonary and disseminated forms of TB. Pathologically confirmed lupus vulgaris (LV) coexisting with lichen scrofulosorum with disseminated TB is presented and discussed. A 12-year-old boy presented with 2 years history of slowly progressive facial plaque and multiple skin colored papules on the neck. Tuberculin skin test was positive with a reading of > 20 mm. Histopathology revealed ulcerated areas with impetiginisation and keratopurulent debris. The entire skin showed pseudoepitheliomatous hyperplasia with numerous granulomas in the superficial dermis consisting of Langhans-type multinucleated macrophages. Lesions responded to anti-tuberculosis therapy (ATT) with residual facial scar. LV and lichen scrofulosurum are two forms of CTB which rarely occurs together. This case is being presented to highlight the occurrence of this rare presentation and the need to institute ATT to prevent scarring.
format Online
Article
Text
id pubmed-7547755
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-75477552020-10-22 Lupus Vulgaris and Lichen Scrofulosorum with Disseminated Tuberculosis Okoh, Nnenna Uzunma Nnaji, T. Onyekonwu, Chinwe L. Emeka, Chika Mary Niger Med J Case Report Cutaneous tuberculosis (CTB) represents only 1%–2% of extrapulmonary forms of tuberculosis (TB). CTB can present in the isolation or coexist with pulmonary and disseminated forms of TB. Pathologically confirmed lupus vulgaris (LV) coexisting with lichen scrofulosorum with disseminated TB is presented and discussed. A 12-year-old boy presented with 2 years history of slowly progressive facial plaque and multiple skin colored papules on the neck. Tuberculin skin test was positive with a reading of > 20 mm. Histopathology revealed ulcerated areas with impetiginisation and keratopurulent debris. The entire skin showed pseudoepitheliomatous hyperplasia with numerous granulomas in the superficial dermis consisting of Langhans-type multinucleated macrophages. Lesions responded to anti-tuberculosis therapy (ATT) with residual facial scar. LV and lichen scrofulosurum are two forms of CTB which rarely occurs together. This case is being presented to highlight the occurrence of this rare presentation and the need to institute ATT to prevent scarring. Wolters Kluwer - Medknow 2020 2020-07-04 /pmc/articles/PMC7547755/ /pubmed/33100470 http://dx.doi.org/10.4103/nmj.NMJ_135_19 Text en Copyright: © 2020 Nigerian Medical Journal http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Okoh, Nnenna Uzunma
Nnaji, T.
Onyekonwu, Chinwe L.
Emeka, Chika Mary
Lupus Vulgaris and Lichen Scrofulosorum with Disseminated Tuberculosis
title Lupus Vulgaris and Lichen Scrofulosorum with Disseminated Tuberculosis
title_full Lupus Vulgaris and Lichen Scrofulosorum with Disseminated Tuberculosis
title_fullStr Lupus Vulgaris and Lichen Scrofulosorum with Disseminated Tuberculosis
title_full_unstemmed Lupus Vulgaris and Lichen Scrofulosorum with Disseminated Tuberculosis
title_short Lupus Vulgaris and Lichen Scrofulosorum with Disseminated Tuberculosis
title_sort lupus vulgaris and lichen scrofulosorum with disseminated tuberculosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547755/
https://www.ncbi.nlm.nih.gov/pubmed/33100470
http://dx.doi.org/10.4103/nmj.NMJ_135_19
work_keys_str_mv AT okohnnennauzunma lupusvulgarisandlichenscrofulosorumwithdisseminatedtuberculosis
AT nnajit lupusvulgarisandlichenscrofulosorumwithdisseminatedtuberculosis
AT onyekonwuchinwel lupusvulgarisandlichenscrofulosorumwithdisseminatedtuberculosis
AT emekachikamary lupusvulgarisandlichenscrofulosorumwithdisseminatedtuberculosis