Cargando…

AmpR Increases the Virulence of Carbapenem-Resistant Klebsiella pneumoniae by Regulating the Initial Step of Capsule Synthesis

BACKGROUND: Non-hypermucoviscous carbapenem-resistant Klebsiella pneumoniae with enhanced virulence lacking hvKP-specific virulence factors is uncommon, and the virulence mechanisms of this organism are not understood. METHODS: Following a retrospective study of carbapenem-resistant K. pneumoniae ba...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Min, Zhang, Jinyong, Li, Jia, Wu, Xianglin, Xiao, Lihua, Liu, Xueyan, Yang, Xiyao, Yang, Liqi, Zou, Quanming, Huang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547782/ https://www.ncbi.nlm.nih.gov/pubmed/33116662 http://dx.doi.org/10.2147/IDR.S269275

Ejemplares similares

The Regulatory Repertoire of Pseudomonas aeruginosa AmpC ß-Lactamase Regulator AmpR Includes Virulence Genes
por: Balasubramanian, Deepak, et al.
Publicado: (2012)

Role of AmpR in the High Expression of the Plasmid-Encoded AmpC β-Lactamase CFE-1
por: Nakano, Ryuichi, et al.
Publicado: (2017)

The Role of nmcR, ampR, and ampD in the Regulation of the Class A Carbapenemase NmcA in Enterobacter ludwigii
por: Nakano, Ryuichi, et al.
Publicado: (2022)

Carbapenem-Resistant Klebsiella pneumoniae: Diversity, Virulence, and Antimicrobial Resistance
por: Elmanakhly, Arwa R, et al.
Publicado: (2022)

Role of Low-Molecular-Mass Penicillin-Binding Proteins, NagZ and AmpR in AmpC β-lactamase Regulation of Yersinia enterocolitica
por: Liu, Chang, et al.
Publicado: (2017)

The functional repertoire of AmpR in the AmpC β-lactamase high expression and decreasing β-lactam and aminoglycosides resistance in ESBL Citrobacter freundii
por: Tariq, Falak Naz, et al.
Publicado: (2023)

Phenotypic and Genotypic Characterization of a Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae ST17-KL38 Clinical Isolate Harboring the Carbapenemase IMP-4
por: He, Jintao, et al.
Publicado: (2022)

Novel Subclone of Carbapenem-Resistant Klebsiella pneumoniae Sequence Type 11 with Enhanced Virulence and Transmissibility, China
por: Zhou, Kai, et al.
Publicado: (2020)

Epidemiological Study of Carbapenem-resistant Klebsiella Pneumoniae
por: Lin, Di, et al.
Publicado: (2018)

Outbreak of KPC-2 Carbapenem-resistant Klebsiella pneumoniae ST76 and Carbapenem-resistant K2 Hypervirulent Klebsiella pneumoniae ST375 strains in Northeast China: molecular and virulent characteristics
por: Su, Shanshan, et al.
Publicado: (2020)

Infection with Carbapenem-resistant Hypervirulent Klebsiella Pneumoniae: clinical, virulence and molecular epidemiological characteristics
por: Li, Linlin, et al.
Publicado: (2023)

Genome Sequence of Klebsiella pneumoniae YBQ, a Clinical Strain Isolated from the Sputum of a Patient with Severe Pneumonia
por: Zou, Jintao, et al.
Publicado: (2020)

Molecular characterization of carbapenem-resistant and virulent plasmids in Klebsiella pneumoniae from patients with bloodstream infections in China
por: Yang, Yongqiang, et al.
Publicado: (2021)

Prevalence of Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae and Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae in China Determined via Mouse Lethality Tests
por: Hu, Dakang, et al.
Publicado: (2022)

Dynamic Epidemiology and Virulence Characteristics of Carbapenem-Resistant Klebsiella pneumoniae in Wenzhou, China from 2003 to 2016
por: Zhao, Yajie, et al.
Publicado: (2020)

Carbapenem-Resistant Klebsiella pneumoniae: Virulence Factors, Molecular Epidemiology and Latest Updates in Treatment Options
por: Karampatakis, Theodoros, et al.
Publicado: (2023)

Rapid Nanopore Assay for Carbapenem-Resistant Klebsiella pneumoniae
por: Niu, Haofu, et al.
Publicado: (2019)

Molecular epidemiology of carbapenem-resistant hypervirulent Klebsiella pneumoniae in China
por: Yang, Xuemei, et al.
Publicado: (2022)

Bactericidal, anti-biofilm, and anti-virulence activity of vitamin C against carbapenem-resistant hypervirulent Klebsiella pneumoniae
por: Xu, Chen, et al.
Publicado: (2022)

Heteroresistance to Amikacin in Carbapenem-Resistant Klebsiella pneumoniae Strains
por: Zhang, Feiyang, et al.
Publicado: (2021)

Limiting and controlling carbapenem-resistant Klebsiella pneumoniae
por: Saidel-Odes, Lisa, et al.
Publicado: (2013)

No Carbapenem Resistance in Pneumonia Caused by Klebsiella Species
por: Yayan, Josef, et al.
Publicado: (2015)

Risk Factors for Carbapenem-resistant Klebsiella pneumoniae Infection and Mortality of Klebsiella pneumoniae Infection
por: Wang, Zhe, et al.
Publicado: (2018)

Risk Factors for Subsequential Carbapenem-Resistant Klebsiella pneumoniae Clinical Infection Among Rectal Carriers with Carbapenem-Resistant Klebsiella pneumoniae
por: Chen, Xia, et al.
Publicado: (2020)

Factors behind the prevalence of carbapenem-resistant Klebsiella pneumoniae in pediatric wards
por: Yang, Yuxin, et al.
Publicado: (2021)

Network Integrative Genomic and Transcriptomic Analysis of Carbapenem-Resistant Klebsiella pneumoniae Strains Identifies Genes for Antibiotic Resistance and Virulence
por: Lee, Muyoung, et al.
Publicado: (2019)

Virulence characterization of Klebsiella pneumoniae and its relation with ESBL and AmpC beta-lactamase associated resistance
por: Soltani, Elghar, et al.
Publicado: (2020)

Impact of Carbapenem Heteroresistance Among Multidrug-Resistant ESBL/AmpC-Producing Klebsiella pneumoniae Clinical Isolates on Antibiotic Treatment in Experimentally Infected Mice
por: Xiong, Yilin, et al.
Publicado: (2021)

Virulence, antimicrobial resistance, and molecular characteristics of carbapenem-resistant Klebsiella pneumoniae in a hospital in Shijiazhuang City from China
por: Guo, Yumei, et al.
Publicado: (2023)

Innate Immune Effectors Play Essential Roles in Acute Respiratory Infection Caused by Klebsiella pneumoniae
por: Liu, Dong, et al.
Publicado: (2020)

Emergence of Ceftazidime–Avibactam Resistance and Decreased Virulence in Carbapenem-Resistant ST11 Klebsiella pneumoniae During Antibiotics Treatment
por: Xu, Mengxin, et al.
Publicado: (2022)

Molecular epidemiology and mechanism of Klebsiella pneumoniae resistance to ertapenem but not to other carbapenems in China
por: Wang, Dongliang, et al.
Publicado: (2022)

Clinical evolution of ST11 carbapenem resistant and hypervirulent Klebsiella pneumoniae
por: Xie, Miaomiao, et al.
Publicado: (2021)

Rapid susceptibility profiling of carbapenem-resistant Klebsiella pneumoniae
por: Mulroney, K. T., et al.
Publicado: (2017)

The Metabolome of Carbapenem-Resistant Klebsiella pneumoniae Infection in Plasma
por: Wen, Zhongwei, et al.
Publicado: (2021)

Carbapenem-Resistant Klebsiella pneumoniae Associated with COVID-19
por: Dumitru, Irina Magdalena, et al.
Publicado: (2021)

Virulence Characteristics of Carbapenem-Resistant Klebsiella pneumoniae Strains from Patients with Necrotizing Skin and Soft Tissue Infections
por: Krapp, Fiorella, et al.
Publicado: (2017)

Genomic Features Associated with the Degree of Phenotypic Resistance to Carbapenems in Carbapenem-Resistant Klebsiella pneumoniae
por: Bulman, Zackery P., et al.
Publicado: (2021)

Within-Host Resistance and Virulence Evolution of a Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae ST11 Under Antibiotic Pressure
por: Zhou, Cong, et al.
Publicado: (2023)

Prediction of Prognosis in Adult Patients With Carbapenem-Resistant Klebsiella pneumoniae Infection
por: Chen, Jihui, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_h4nrh3bk09o13f3v5i12jpfm2g