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Development of Rifapentine-Loaded PLGA-Based Nanoparticles: In vitro Characterisation and in vivo Study in Mice

BACKGROUND: Tuberculosis (TB) is a leading cause of death amongst infectious diseases. The poor response to antitubercular agents necessitates the long-term use of high drug doses, resulting in low patient compliance, which is the main reason for chemotherapy failure and contributes to the developme...

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Detalles Bibliográficos
Autores principales: Liang, Qiuzhen, Xiang, Haibin, Li, Xinyu, Luo, Chunxia, Ma, Xuehong, Zhao, Wenhui, Chen, Jiangtao, Tian, Zheng, Li, Xinxia, Song, Xinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547843/
https://www.ncbi.nlm.nih.gov/pubmed/33116484
http://dx.doi.org/10.2147/IJN.S257758