CaMKIIδC Drives Early Adaptive Ca(2+) Change and Late Eccentric Cardiac Hypertrophy

CaMKII (Ca(2+)-Calmodulin dependent protein kinase) δC activation is implicated in pathological progression of heart failure (HF) and CaMKIIδC transgenic mice rapidly develop HF and arrhythmias. However, little is known about early spatio-temporal Ca(2+) handling and CaMKII activation in hypertrophy...

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Detalles Bibliográficos
Autores principales: Ljubojevic-Holzer, Senka, Herren, Anthony W., Djalinac, Natasa, Voglhuber, Julia, Morotti, Stefano, Holzer, Michael, Wood, Brent M., Abdellatif, Mahmoud, Matzer, Ingrid, Sacherer, Michael, Radulovic, Snjezana, Wallner, Markus, Ivanov, Milan, Wagner, Stefan, Sossalla, Samuel, von Lewinski, Dirk, Pieske, Burkert, Brown, Joan Heller, Sedej, Simon, Bossuyt, Julie, Bers, Donald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547876/
https://www.ncbi.nlm.nih.gov/pubmed/32821022
http://dx.doi.org/10.1161/CIRCRESAHA.120.316947

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