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A novel strategy for molecular interfaces optimization: The case of Ferritin-Transferrin receptor interaction
Protein-protein interactions regulate almost all cellular functions and rely on a fine tune of surface amino acids properties involved on both molecular partners. The disruption of a molecular association can be caused even by a single residue mutation, often leading to a pathological modification o...
Autores principales: | Di Rienzo, Lorenzo, Milanetti, Edoardo, Testi, Claudia, Montemiglio, Linda Celeste, Baiocco, Paola, Boffi, Alberto, Ruocco, Giancarlo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548301/ https://www.ncbi.nlm.nih.gov/pubmed/33101606 http://dx.doi.org/10.1016/j.csbj.2020.09.020 |
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