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Safety and immunogenicity evaluation of recombinant BCG vaccine against respiratory syncytial virus in a randomized, double-blind, placebo-controlled phase I clinical trial
BACKGROUND: Respiratory syncytial virus (RSV) is responsible for most respiratory tract infections and hospitalizations in infants and represents a significant economic burden for public health. The development of a safe, effective, and affordable vaccine is a priority for the WHO. METHODS: We condu...
Autores principales: | Abarca, Katia, Rey-Jurado, Emma, Muñoz-Durango, Natalia, Vázquez, Yaneisi, Soto, Jorge A., Gálvez, Nicolás M.S., Valdés-Ferrada, Javier, Iturriaga, Carolina, Urzúa, Marcela, Borzutzky, Arturo, Cerda, Jaime, Villarroel, Luis, Madrid, Victoria, González, Pablo A., González-Aramundiz, José V., Bueno, Susan M., Kalergis, Alexis M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548429/ https://www.ncbi.nlm.nih.gov/pubmed/33073219 http://dx.doi.org/10.1016/j.eclinm.2020.100517 |
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