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Cancer Risk Assessment for Workers Exposed to Pollution Source, a Petrochemical Company, Iran

BACKGROUND: Air pollution have led to severe problem of adverse health effect in the world. This study aimed to conduct the health risk assessment, cancer risk analysis, and non-cancer risk for exposure to volatile organic compounds (VOCs) and hydrogen sulfide (H ( 2 ) S) in petrochemical industry....

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Autores principales: HARATI, Bahram, SHAHTAHERI, Seyed Jamaleddin, YOUSEFI, Hossein Ali, HARATI, Ali, ASKARI, Ali, ABDOLMOHAMADI, Nabi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548477/
https://www.ncbi.nlm.nih.gov/pubmed/33083300
http://dx.doi.org/10.18502/ijph.v49i7.3587
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author HARATI, Bahram
SHAHTAHERI, Seyed Jamaleddin
YOUSEFI, Hossein Ali
HARATI, Ali
ASKARI, Ali
ABDOLMOHAMADI, Nabi
author_facet HARATI, Bahram
SHAHTAHERI, Seyed Jamaleddin
YOUSEFI, Hossein Ali
HARATI, Ali
ASKARI, Ali
ABDOLMOHAMADI, Nabi
author_sort HARATI, Bahram
collection PubMed
description BACKGROUND: Air pollution have led to severe problem of adverse health effect in the world. This study aimed to conduct the health risk assessment, cancer risk analysis, and non-cancer risk for exposure to volatile organic compounds (VOCs) and hydrogen sulfide (H ( 2 ) S) in petrochemical industry. METHODS: In this cross-sectional research, 123 samples were collected in the ambient air in Iran during winter 2016. For sampling and analysis of VOCs and H ( 2 ) S, 3 methods (numbers 1500, 1501, and 6013) presented by the National Institute of Occupational Safety and Health (NIOSH) were used. For determination of risk assessment of chemical pollutants, semi-quantitative method presented by the Occupational Safety and Health Division, Singapore was used. Finally, for calculation of cancer risk analysis, Chronic Daily Intake (CDI) and calculation of non-cancer risk, Exposure Concentration (EC) were used. RESULTS: Average concentration of benzene (2.12±0.95) in breathing zone of workers were higher than the Threshold Limit Values-Time Weighted Average (TLV-TWA) (P<0.05). Among chemical substance, benzene had very high rank of risk in petrochemical industry. Rank of risk for H ( 2 ) S, toluene, and xylene present in the breathing zone of workers was low. The mean cancer risk for workers exposed to benzene was estimated 8.78×10(−3,) in other words, 8.7 cancer per 1000 i.e. higher than the acceptable standard of 10(−6). In our study, non-cancer risk for BTX was higher than the acceptable standard of 1. CONCLUSION: In particular, overall cancer and toxic risk can be associated with long term exposure to benzene.
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spelling pubmed-75484772020-10-19 Cancer Risk Assessment for Workers Exposed to Pollution Source, a Petrochemical Company, Iran HARATI, Bahram SHAHTAHERI, Seyed Jamaleddin YOUSEFI, Hossein Ali HARATI, Ali ASKARI, Ali ABDOLMOHAMADI, Nabi Iran J Public Health Original Article BACKGROUND: Air pollution have led to severe problem of adverse health effect in the world. This study aimed to conduct the health risk assessment, cancer risk analysis, and non-cancer risk for exposure to volatile organic compounds (VOCs) and hydrogen sulfide (H ( 2 ) S) in petrochemical industry. METHODS: In this cross-sectional research, 123 samples were collected in the ambient air in Iran during winter 2016. For sampling and analysis of VOCs and H ( 2 ) S, 3 methods (numbers 1500, 1501, and 6013) presented by the National Institute of Occupational Safety and Health (NIOSH) were used. For determination of risk assessment of chemical pollutants, semi-quantitative method presented by the Occupational Safety and Health Division, Singapore was used. Finally, for calculation of cancer risk analysis, Chronic Daily Intake (CDI) and calculation of non-cancer risk, Exposure Concentration (EC) were used. RESULTS: Average concentration of benzene (2.12±0.95) in breathing zone of workers were higher than the Threshold Limit Values-Time Weighted Average (TLV-TWA) (P<0.05). Among chemical substance, benzene had very high rank of risk in petrochemical industry. Rank of risk for H ( 2 ) S, toluene, and xylene present in the breathing zone of workers was low. The mean cancer risk for workers exposed to benzene was estimated 8.78×10(−3,) in other words, 8.7 cancer per 1000 i.e. higher than the acceptable standard of 10(−6). In our study, non-cancer risk for BTX was higher than the acceptable standard of 1. CONCLUSION: In particular, overall cancer and toxic risk can be associated with long term exposure to benzene. Tehran University of Medical Sciences 2020-07 /pmc/articles/PMC7548477/ /pubmed/33083300 http://dx.doi.org/10.18502/ijph.v49i7.3587 Text en Copyright© Iranian Public Health Association & Tehran University of Medical Sciences http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
HARATI, Bahram
SHAHTAHERI, Seyed Jamaleddin
YOUSEFI, Hossein Ali
HARATI, Ali
ASKARI, Ali
ABDOLMOHAMADI, Nabi
Cancer Risk Assessment for Workers Exposed to Pollution Source, a Petrochemical Company, Iran
title Cancer Risk Assessment for Workers Exposed to Pollution Source, a Petrochemical Company, Iran
title_full Cancer Risk Assessment for Workers Exposed to Pollution Source, a Petrochemical Company, Iran
title_fullStr Cancer Risk Assessment for Workers Exposed to Pollution Source, a Petrochemical Company, Iran
title_full_unstemmed Cancer Risk Assessment for Workers Exposed to Pollution Source, a Petrochemical Company, Iran
title_short Cancer Risk Assessment for Workers Exposed to Pollution Source, a Petrochemical Company, Iran
title_sort cancer risk assessment for workers exposed to pollution source, a petrochemical company, iran
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548477/
https://www.ncbi.nlm.nih.gov/pubmed/33083300
http://dx.doi.org/10.18502/ijph.v49i7.3587
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