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Structural and Functional Characterization of a Unique AP Endonuclease From Deinococcus radiodurans

Various endogenous and exogenous agents cause DNA damage, including apurinic/apyrimidinic (AP) sites. Due to their cytotoxic effects, AP sites are usually cleaved by AP endonuclease through the base excision repair (BER) pathway. Deinococcus radiodurans, an extraordinary radiation-resistant bacteriu...

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Detalles Bibliográficos
Autores principales: He, Yuan, Wang, Yiyi, Qin, Chen, Xu, Ying, Cheng, Kaiying, Xu, Hong, Tian, Bing, Zhao, Ye, Wang, Liangyan, Hua, Yuejin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548837/
https://www.ncbi.nlm.nih.gov/pubmed/33117296
http://dx.doi.org/10.3389/fmicb.2020.01178