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Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection

Coronaviruses have caused several zoonotic infections in the past two decades, leading to significant morbidity and mortality globally. Balanced regulation of cell death and inflammatory immune responses is essential to promote protection against coronavirus infection; however, the underlying mechan...

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Detalles Bibliográficos
Autores principales:	Zheng, Min, Williams, Evan Peter, Malireddi, R. K. Subbarao, Karki, Rajendra, Banoth, Balaji, Burton, Amanda, Webby, Richard, Channappanavar, Rudragouda, Jonsson, Colleen Beth, Kanneganti, Thirumala-Devi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549031/ https://www.ncbi.nlm.nih.gov/pubmed/32763970 http://dx.doi.org/10.1074/jbc.RA120.015036

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