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Expression profiling of DNA methyl transferase I (DNMT1) and efficacy of a DNA-hypomethylating agent (decitabine) in combination with chemotherapy in osteosarcoma

BACKGROUND: Abnormality in the DNA methylation process is one of the hallmarks of cancer. Emerging evidence strongly supports the idea that defects in DNA methyl transferases (DNMTs) are involved in tumor development and progression. This alteration has major effects at the transcription level of va...

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Detalles Bibliográficos
Autores principales:	Chaiyawat, Parunya, Sirikaew, Nutnicha, Budprom, Piyaporn, Klangjorhor, Jeerawan, Phanphaisarn, Areerak, Teeyakasem, Pimpisa, Settakorn, Jongkolnee, Pruksakorn, Dumnoensun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549121/ https://www.ncbi.nlm.nih.gov/pubmed/33072501 http://dx.doi.org/10.1016/j.jbo.2020.100321

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