Cargando…
First Complete Genome Sequences of Janthinobacterium lividum EIF1 and EIF2 and Their Comparative Genome Analysis
We present the first two complete genomes of the Janthinobacterium lividum species, namely strains EIF1 and EIF2, which both possess the ability to synthesize violacein. The violet pigment violacein is a secondary metabolite with antibacterial, antifungal, antiviral, and antitumoral properties. Both...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549134/ https://www.ncbi.nlm.nih.gov/pubmed/32658247 http://dx.doi.org/10.1093/gbe/evaa148 |
_version_ | 1783592743012925440 |
---|---|
author | Friedrich, Ines Hollensteiner, Jacqueline Schneider, Dominik Poehlein, Anja Hertel, Robert Daniel, Rolf |
author_facet | Friedrich, Ines Hollensteiner, Jacqueline Schneider, Dominik Poehlein, Anja Hertel, Robert Daniel, Rolf |
author_sort | Friedrich, Ines |
collection | PubMed |
description | We present the first two complete genomes of the Janthinobacterium lividum species, namely strains EIF1 and EIF2, which both possess the ability to synthesize violacein. The violet pigment violacein is a secondary metabolite with antibacterial, antifungal, antiviral, and antitumoral properties. Both strains were isolated from environmental oligotrophic water ponds in Göttingen. The strains were phylogenetically classified by average nucleotide identity (ANI) analysis and showed a species assignment to J. lividum with 97.72% (EIF1) and 97.66% (EIF2) identity. These are the first complete genome sequences of strains belonging to the species J. lividum. The genome of strain EIF1 consists of one circular chromosome (6,373,589 bp) with a GC-content of 61.98%. The genome contains 5,551 coding sequences, 122 rRNAs, 93 tRNAs, and 1 tm-RNA. The genome of EIF2 comprises one circular chromosome (6,399,352 bp) with a GC-content of 61.63% and a circular plasmid p356839 (356,839 bp) with a GC-content of 57.21%. The chromosome encodes 5,691 coding sequences, 122 rRNAs, 93 tRNAs, and 1 tm-RNA and the plasmid harbors 245 coding sequences. In addition to the highly conserved chromosomally encoded violacein operon, the plasmid comprises a nonribosomal peptide synthetase cluster with similarity to xenoamicin, which is a bioactive compound effective against protozoan parasites. |
format | Online Article Text |
id | pubmed-7549134 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-75491342020-10-16 First Complete Genome Sequences of Janthinobacterium lividum EIF1 and EIF2 and Their Comparative Genome Analysis Friedrich, Ines Hollensteiner, Jacqueline Schneider, Dominik Poehlein, Anja Hertel, Robert Daniel, Rolf Genome Biol Evol Genome Report We present the first two complete genomes of the Janthinobacterium lividum species, namely strains EIF1 and EIF2, which both possess the ability to synthesize violacein. The violet pigment violacein is a secondary metabolite with antibacterial, antifungal, antiviral, and antitumoral properties. Both strains were isolated from environmental oligotrophic water ponds in Göttingen. The strains were phylogenetically classified by average nucleotide identity (ANI) analysis and showed a species assignment to J. lividum with 97.72% (EIF1) and 97.66% (EIF2) identity. These are the first complete genome sequences of strains belonging to the species J. lividum. The genome of strain EIF1 consists of one circular chromosome (6,373,589 bp) with a GC-content of 61.98%. The genome contains 5,551 coding sequences, 122 rRNAs, 93 tRNAs, and 1 tm-RNA. The genome of EIF2 comprises one circular chromosome (6,399,352 bp) with a GC-content of 61.63% and a circular plasmid p356839 (356,839 bp) with a GC-content of 57.21%. The chromosome encodes 5,691 coding sequences, 122 rRNAs, 93 tRNAs, and 1 tm-RNA and the plasmid harbors 245 coding sequences. In addition to the highly conserved chromosomally encoded violacein operon, the plasmid comprises a nonribosomal peptide synthetase cluster with similarity to xenoamicin, which is a bioactive compound effective against protozoan parasites. Oxford University Press 2020-07-13 /pmc/articles/PMC7549134/ /pubmed/32658247 http://dx.doi.org/10.1093/gbe/evaa148 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Genome Report Friedrich, Ines Hollensteiner, Jacqueline Schneider, Dominik Poehlein, Anja Hertel, Robert Daniel, Rolf First Complete Genome Sequences of Janthinobacterium lividum EIF1 and EIF2 and Their Comparative Genome Analysis |
title | First Complete Genome Sequences of Janthinobacterium lividum EIF1 and EIF2 and Their Comparative Genome Analysis |
title_full | First Complete Genome Sequences of Janthinobacterium lividum EIF1 and EIF2 and Their Comparative Genome Analysis |
title_fullStr | First Complete Genome Sequences of Janthinobacterium lividum EIF1 and EIF2 and Their Comparative Genome Analysis |
title_full_unstemmed | First Complete Genome Sequences of Janthinobacterium lividum EIF1 and EIF2 and Their Comparative Genome Analysis |
title_short | First Complete Genome Sequences of Janthinobacterium lividum EIF1 and EIF2 and Their Comparative Genome Analysis |
title_sort | first complete genome sequences of janthinobacterium lividum eif1 and eif2 and their comparative genome analysis |
topic | Genome Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549134/ https://www.ncbi.nlm.nih.gov/pubmed/32658247 http://dx.doi.org/10.1093/gbe/evaa148 |
work_keys_str_mv | AT friedrichines firstcompletegenomesequencesofjanthinobacteriumlividumeif1andeif2andtheircomparativegenomeanalysis AT hollensteinerjacqueline firstcompletegenomesequencesofjanthinobacteriumlividumeif1andeif2andtheircomparativegenomeanalysis AT schneiderdominik firstcompletegenomesequencesofjanthinobacteriumlividumeif1andeif2andtheircomparativegenomeanalysis AT poehleinanja firstcompletegenomesequencesofjanthinobacteriumlividumeif1andeif2andtheircomparativegenomeanalysis AT hertelrobert firstcompletegenomesequencesofjanthinobacteriumlividumeif1andeif2andtheircomparativegenomeanalysis AT danielrolf firstcompletegenomesequencesofjanthinobacteriumlividumeif1andeif2andtheircomparativegenomeanalysis |