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Efficiently cleaved HIV-1 envelopes: can they be important for vaccine immunogen development?

The enormous diversity of HIV-1 is a significant impediment in selecting envelopes (Envs) that can be suitable for designing vaccine immunogens. While tremendous progress has been made in developing soluble, trimeric, native-like Env proteins, those that have elicited neutralizing antibodies (Abs) i...

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Detalles Bibliográficos
Autores principales: Das, Supratik, Kumar, Rajesh, Ahmed, Shubbir, Parray, Hilal Ahmad, Samal, Sweety
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549152/
https://www.ncbi.nlm.nih.gov/pubmed/33103053
http://dx.doi.org/10.1177/2515135520957763