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Discovery of FNDR-20123, a histone deacetylase inhibitor for the treatment of Plasmodium falciparum malaria

BACKGROUND: Emergence of anti-malarial drug resistance and perpetual increase in malaria incidence necessitates the development of novel anti-malarials. Histone deacetylases (HDAC) has been shown to be a promising target for malaria, despite this, there are no HDAC inhibitors in clinical trials for...

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Detalles Bibliográficos
Autores principales:	Potluri, Vijay, Shandil, Radha K., Gavara, R., Sambasivam, Ganesh, Campo, Brice, Wittlin, Sergio, Narayanan, Shridhar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549214/ https://www.ncbi.nlm.nih.gov/pubmed/33046062 http://dx.doi.org/10.1186/s12936-020-03421-3

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