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miR-21 regulates immunosuppression mediated by myeloid-derived suppressor cells by impairing RUNX1-YAP interaction in lung cancer

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) are known suppressors of antitumor immunity and contribute to immunosuppressive microenvironment during tumor development including lung cancer. Accumulating evidence shows microRNAs (miRNAs) affect tumor-expanded MDSC accumulation and function in...

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Detalles Bibliográficos
Autores principales:	Meng, Guangping, Wei, Jinying, Wang, Yanjun, Qu, Danhua, Zhang, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549228/ https://www.ncbi.nlm.nih.gov/pubmed/33061847 http://dx.doi.org/10.1186/s12935-020-01555-7

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