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AT101-Loaded Cubosomes as an Alternative for Improved Glioblastoma Therapy

INTRODUCTION: AT101, the R-(-)-enantiomer of the cottonseed-derived polyphenol gossypol, is a promising drug in glioblastoma multiforme (GBM) therapy due to its ability to trigger autophagic cell death but also to facilitate apoptosis in tumor cells. It does have some limitations such as poor solubi...

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Detalles Bibliográficos
Autores principales: Flak, Dorota K, Adamski, Vivian, Nowaczyk, Grzegorz, Szutkowski, Kosma, Synowitz, Michael, Jurga, Stefan, Held-Feindt, Janka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549312/
https://www.ncbi.nlm.nih.gov/pubmed/33116479
http://dx.doi.org/10.2147/IJN.S265061