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AT101-Loaded Cubosomes as an Alternative for Improved Glioblastoma Therapy
INTRODUCTION: AT101, the R-(-)-enantiomer of the cottonseed-derived polyphenol gossypol, is a promising drug in glioblastoma multiforme (GBM) therapy due to its ability to trigger autophagic cell death but also to facilitate apoptosis in tumor cells. It does have some limitations such as poor solubi...
Autores principales: | Flak, Dorota K, Adamski, Vivian, Nowaczyk, Grzegorz, Szutkowski, Kosma, Synowitz, Michael, Jurga, Stefan, Held-Feindt, Janka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549312/ https://www.ncbi.nlm.nih.gov/pubmed/33116479 http://dx.doi.org/10.2147/IJN.S265061 |
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