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Survival following intentional succinylcholine injection for self-harm

Succinylcholine is a short-acting depolarizing neuromuscular blocking agent. We describe a case where the above drug was employed for self-harm by a health-care worker. The patient, a 28-year-old female, was brought to the emergency department (ED) in impending respiratory arrest and altered mental...

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Autores principales: Kunhahamed, Meenhas Oravil, Thomas, Vimal Koshy, Abraham, Siju Varghese, Palatty, Babu Urumese, Kallivalappil, Shibu C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549520/
https://www.ncbi.nlm.nih.gov/pubmed/33089028
http://dx.doi.org/10.4103/2452-2473.297468
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author Kunhahamed, Meenhas Oravil
Thomas, Vimal Koshy
Abraham, Siju Varghese
Palatty, Babu Urumese
Kallivalappil, Shibu C.
author_facet Kunhahamed, Meenhas Oravil
Thomas, Vimal Koshy
Abraham, Siju Varghese
Palatty, Babu Urumese
Kallivalappil, Shibu C.
author_sort Kunhahamed, Meenhas Oravil
collection PubMed
description Succinylcholine is a short-acting depolarizing neuromuscular blocking agent. We describe a case where the above drug was employed for self-harm by a health-care worker. The patient, a 28-year-old female, was brought to the emergency department (ED) in impending respiratory arrest and altered mental status. On arrival, she had hypoxia, bradycardia, and hypotension. Although the cause for rapid deterioration in this patient was unknown, the ED physician still went ahead by resuscitating the patient's airway, breathing, and circulation. During the course of resuscitation, information was received that an empty ampoule of succinylcholine was recovered from her bathroom. Further clinical examination and laboratory investigations led the treating physicians to suspect deliberate intravenous injection of succinylcholine. She was mechanically ventilated and monitored in the critical care unit. Targeted temperature management was initiated in the ED and was continued for 24 h. The patient was discharged from the hospital without any neurological deficits after 4 days. Patients with acute poisoning are one of the major encounters in ED, and this case highlights the possibility of anesthetic drug misuse in any health-care workers coming to the ED with sudden cardiac arrest, altered sensorium, or abnormal vitals. This is the first report describing the survival of a patient following intentional succinylcholine injection for self-harm.
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spelling pubmed-75495202020-10-20 Survival following intentional succinylcholine injection for self-harm Kunhahamed, Meenhas Oravil Thomas, Vimal Koshy Abraham, Siju Varghese Palatty, Babu Urumese Kallivalappil, Shibu C. Turk J Emerg Med Case Report Succinylcholine is a short-acting depolarizing neuromuscular blocking agent. We describe a case where the above drug was employed for self-harm by a health-care worker. The patient, a 28-year-old female, was brought to the emergency department (ED) in impending respiratory arrest and altered mental status. On arrival, she had hypoxia, bradycardia, and hypotension. Although the cause for rapid deterioration in this patient was unknown, the ED physician still went ahead by resuscitating the patient's airway, breathing, and circulation. During the course of resuscitation, information was received that an empty ampoule of succinylcholine was recovered from her bathroom. Further clinical examination and laboratory investigations led the treating physicians to suspect deliberate intravenous injection of succinylcholine. She was mechanically ventilated and monitored in the critical care unit. Targeted temperature management was initiated in the ED and was continued for 24 h. The patient was discharged from the hospital without any neurological deficits after 4 days. Patients with acute poisoning are one of the major encounters in ED, and this case highlights the possibility of anesthetic drug misuse in any health-care workers coming to the ED with sudden cardiac arrest, altered sensorium, or abnormal vitals. This is the first report describing the survival of a patient following intentional succinylcholine injection for self-harm. Wolters Kluwer - Medknow 2020-10-07 /pmc/articles/PMC7549520/ /pubmed/33089028 http://dx.doi.org/10.4103/2452-2473.297468 Text en Copyright: © 2020 Turkish Journal of Emergency Medicine http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Kunhahamed, Meenhas Oravil
Thomas, Vimal Koshy
Abraham, Siju Varghese
Palatty, Babu Urumese
Kallivalappil, Shibu C.
Survival following intentional succinylcholine injection for self-harm
title Survival following intentional succinylcholine injection for self-harm
title_full Survival following intentional succinylcholine injection for self-harm
title_fullStr Survival following intentional succinylcholine injection for self-harm
title_full_unstemmed Survival following intentional succinylcholine injection for self-harm
title_short Survival following intentional succinylcholine injection for self-harm
title_sort survival following intentional succinylcholine injection for self-harm
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549520/
https://www.ncbi.nlm.nih.gov/pubmed/33089028
http://dx.doi.org/10.4103/2452-2473.297468
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