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The impact of social distancing on COVID19 spread: State of Georgia case study

As the spread of COVID19 in the US continues to grow, local and state officials face difficult decisions about when and how to transition to a “new normal.” The goal of this study is to project the number of COVID19 infections and resulting severe outcomes, and the need for hospital capacity under s...

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Autores principales: Keskinocak, Pinar, Oruc, Buse Eylul, Baxter, Arden, Asplund, John, Serban, Nicoleta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549801/
https://www.ncbi.nlm.nih.gov/pubmed/33045008
http://dx.doi.org/10.1371/journal.pone.0239798
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author Keskinocak, Pinar
Oruc, Buse Eylul
Baxter, Arden
Asplund, John
Serban, Nicoleta
author_facet Keskinocak, Pinar
Oruc, Buse Eylul
Baxter, Arden
Asplund, John
Serban, Nicoleta
author_sort Keskinocak, Pinar
collection PubMed
description As the spread of COVID19 in the US continues to grow, local and state officials face difficult decisions about when and how to transition to a “new normal.” The goal of this study is to project the number of COVID19 infections and resulting severe outcomes, and the need for hospital capacity under social distancing, particularly, shelter-in-place and voluntary quarantine for the State of Georgia. We developed an agent-based simulation model to project the infection spread. The model utilizes COVID19-specific parameters and data from Georgia on population interactions and demographics. The simulation study covered a seven and a half-month period, testing different social distancing scenarios, including baselines (no-intervention or school closure only) and combinations of shelter-in-place and voluntary quarantine with different timelines and compliance levels. The following outcomes are compared at the state and community levels: the number and percentage of cumulative and daily new symptomatic and asymptomatic infections, hospitalizations, and deaths; COVID19-related demand for hospital beds, ICU beds, and ventilators. The results suggest that shelter-in-place followed by voluntary quarantine reduced peak infections from approximately 180K under no intervention and 113K under school closure, respectively, to below 53K, and delayed the peak from April to July or later. Increasing shelter-in-place duration from four to five weeks yielded 2–9% and 3–11% decrease in cumulative infection and deaths, respectively. Regardless of the shelter-in-place duration, increasing voluntary quarantine compliance decreased daily new infections from almost 53K to 25K, and decreased cumulative infections by about 50%. The cumulative number of deaths ranged from 6,660 to 19,430 under different scenarios. Peak infection date varied across scenarios and counties; on average, increasing shelter-in-place duration delayed the peak day by 6 days. Overall, shelter-in-place followed by voluntary quarantine substantially reduced COVID19 infections, healthcare resource needs, and severe outcomes.
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spelling pubmed-75498012020-10-20 The impact of social distancing on COVID19 spread: State of Georgia case study Keskinocak, Pinar Oruc, Buse Eylul Baxter, Arden Asplund, John Serban, Nicoleta PLoS One Research Article As the spread of COVID19 in the US continues to grow, local and state officials face difficult decisions about when and how to transition to a “new normal.” The goal of this study is to project the number of COVID19 infections and resulting severe outcomes, and the need for hospital capacity under social distancing, particularly, shelter-in-place and voluntary quarantine for the State of Georgia. We developed an agent-based simulation model to project the infection spread. The model utilizes COVID19-specific parameters and data from Georgia on population interactions and demographics. The simulation study covered a seven and a half-month period, testing different social distancing scenarios, including baselines (no-intervention or school closure only) and combinations of shelter-in-place and voluntary quarantine with different timelines and compliance levels. The following outcomes are compared at the state and community levels: the number and percentage of cumulative and daily new symptomatic and asymptomatic infections, hospitalizations, and deaths; COVID19-related demand for hospital beds, ICU beds, and ventilators. The results suggest that shelter-in-place followed by voluntary quarantine reduced peak infections from approximately 180K under no intervention and 113K under school closure, respectively, to below 53K, and delayed the peak from April to July or later. Increasing shelter-in-place duration from four to five weeks yielded 2–9% and 3–11% decrease in cumulative infection and deaths, respectively. Regardless of the shelter-in-place duration, increasing voluntary quarantine compliance decreased daily new infections from almost 53K to 25K, and decreased cumulative infections by about 50%. The cumulative number of deaths ranged from 6,660 to 19,430 under different scenarios. Peak infection date varied across scenarios and counties; on average, increasing shelter-in-place duration delayed the peak day by 6 days. Overall, shelter-in-place followed by voluntary quarantine substantially reduced COVID19 infections, healthcare resource needs, and severe outcomes. Public Library of Science 2020-10-12 /pmc/articles/PMC7549801/ /pubmed/33045008 http://dx.doi.org/10.1371/journal.pone.0239798 Text en © 2020 Keskinocak et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Keskinocak, Pinar
Oruc, Buse Eylul
Baxter, Arden
Asplund, John
Serban, Nicoleta
The impact of social distancing on COVID19 spread: State of Georgia case study
title The impact of social distancing on COVID19 spread: State of Georgia case study
title_full The impact of social distancing on COVID19 spread: State of Georgia case study
title_fullStr The impact of social distancing on COVID19 spread: State of Georgia case study
title_full_unstemmed The impact of social distancing on COVID19 spread: State of Georgia case study
title_short The impact of social distancing on COVID19 spread: State of Georgia case study
title_sort impact of social distancing on covid19 spread: state of georgia case study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549801/
https://www.ncbi.nlm.nih.gov/pubmed/33045008
http://dx.doi.org/10.1371/journal.pone.0239798
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