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First Australian Case of Good Recovery of a COVID-19 Patient With Severe Neurological Symptoms Post Prolonged Hospitalization

A case of a 75-year-old man with COVID-19, severe neurological symptoms (acute stroke-like symptoms and signs and full recovery after a prolonged hospital stay), and intracranial hypertension is discussed with an in-depth review of his clinical features, biochemistry, haematology, highlighting the r...

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Detalles Bibliográficos
Autores principales: Wijeratne, Tissa, Sales, Carmela A, Crewther, Sheila G, Nguyen, Vinh, Karimi, Leila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549849/
https://www.ncbi.nlm.nih.gov/pubmed/33062489
http://dx.doi.org/10.7759/cureus.10366
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author Wijeratne, Tissa
Sales, Carmela A
Crewther, Sheila G
Nguyen, Vinh
Karimi, Leila
author_facet Wijeratne, Tissa
Sales, Carmela A
Crewther, Sheila G
Nguyen, Vinh
Karimi, Leila
author_sort Wijeratne, Tissa
collection PubMed
description A case of a 75-year-old man with COVID-19, severe neurological symptoms (acute stroke-like symptoms and signs and full recovery after a prolonged hospital stay), and intracranial hypertension is discussed with an in-depth review of his clinical features, biochemistry, haematology, highlighting the relationship between changes in neutrophil-lymphocyte ratio, C-reactive protein level, D-dimer level, and the clinical onset of acute ischemic stroke-like symptoms in the setting of COVID-19 and major neurological manifestations. This is the first such case reported in Australia to date. This case also illustrates the recovery of a patient with COVID-19 complicated with severe neurological symptoms (acute ischemic stroke-like symptoms) during the prolonged intensive care unit stay (at day 26) followed by slow neurorehabilitation and normal recovery from both respiratory and neurological involvement. The onset of acute stroke-like symptoms appears to be closely associated with changes of neutrophil-lymphocyte ratio and in C-reactive protein, and D-dimer levels.
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spelling pubmed-75498492020-10-13 First Australian Case of Good Recovery of a COVID-19 Patient With Severe Neurological Symptoms Post Prolonged Hospitalization Wijeratne, Tissa Sales, Carmela A Crewther, Sheila G Nguyen, Vinh Karimi, Leila Cureus Internal Medicine A case of a 75-year-old man with COVID-19, severe neurological symptoms (acute stroke-like symptoms and signs and full recovery after a prolonged hospital stay), and intracranial hypertension is discussed with an in-depth review of his clinical features, biochemistry, haematology, highlighting the relationship between changes in neutrophil-lymphocyte ratio, C-reactive protein level, D-dimer level, and the clinical onset of acute ischemic stroke-like symptoms in the setting of COVID-19 and major neurological manifestations. This is the first such case reported in Australia to date. This case also illustrates the recovery of a patient with COVID-19 complicated with severe neurological symptoms (acute ischemic stroke-like symptoms) during the prolonged intensive care unit stay (at day 26) followed by slow neurorehabilitation and normal recovery from both respiratory and neurological involvement. The onset of acute stroke-like symptoms appears to be closely associated with changes of neutrophil-lymphocyte ratio and in C-reactive protein, and D-dimer levels. Cureus 2020-09-10 /pmc/articles/PMC7549849/ /pubmed/33062489 http://dx.doi.org/10.7759/cureus.10366 Text en Copyright © 2020, Wijeratne et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Wijeratne, Tissa
Sales, Carmela A
Crewther, Sheila G
Nguyen, Vinh
Karimi, Leila
First Australian Case of Good Recovery of a COVID-19 Patient With Severe Neurological Symptoms Post Prolonged Hospitalization
title First Australian Case of Good Recovery of a COVID-19 Patient With Severe Neurological Symptoms Post Prolonged Hospitalization
title_full First Australian Case of Good Recovery of a COVID-19 Patient With Severe Neurological Symptoms Post Prolonged Hospitalization
title_fullStr First Australian Case of Good Recovery of a COVID-19 Patient With Severe Neurological Symptoms Post Prolonged Hospitalization
title_full_unstemmed First Australian Case of Good Recovery of a COVID-19 Patient With Severe Neurological Symptoms Post Prolonged Hospitalization
title_short First Australian Case of Good Recovery of a COVID-19 Patient With Severe Neurological Symptoms Post Prolonged Hospitalization
title_sort first australian case of good recovery of a covid-19 patient with severe neurological symptoms post prolonged hospitalization
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549849/
https://www.ncbi.nlm.nih.gov/pubmed/33062489
http://dx.doi.org/10.7759/cureus.10366
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