JAK-STAT Domain Enhanced MUC1-CAR-T Cells Induced Esophageal Cancer Elimination

PURPOSE: Chimeric antigen receptor (CAR)-T cells have shown to play a vital role in anti-tumor functions in hematological malignancies, but have poor efficacy in solid tumors. To improve the activation and proliferation of CAR-T cell in solid tumors, we constructed an enhanced CAR-T cells to increas...

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Detalles Bibliográficos
Autores principales: Zhang, Heng, Zhao, Hui, He, Xiaolei, Xi, Feng, Liu, Jiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549884/
https://www.ncbi.nlm.nih.gov/pubmed/33116840
http://dx.doi.org/10.2147/CMAR.S264358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549884/
https://www.ncbi.nlm.nih.gov/pubmed/33116840
http://dx.doi.org/10.2147/CMAR.S264358

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