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Virulent infection of outbred Hartley guinea pigs with recombinant Pichinde virus as a surrogate small animal model for human Lassa fever

Arenaviruses, such as Lassa virus (LASV), can cause severe and fatal hemorrhagic fevers (e.g., Lassa fever, LF) in humans with no vaccines or therapeutics. Research on arenavirus-induced hemorrhagic fevers (AHFs) has been hampered by the highly virulent nature of these viral pathogens, which require...

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Detalles Bibliográficos
Autores principales: Lan, Shuiyun, Shieh, Wun-Ju, Huang, Qinfeng, Zaki, Sherif R., Liang, Yuying, Ly, Hinh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549944/
https://www.ncbi.nlm.nih.gov/pubmed/32799623
http://dx.doi.org/10.1080/21505594.2020.1809328