Identification of FDA-approved antivirulence drugs targeting the Pseudomonas aeruginosa quorum sensing effector protein PqsE

The ability of the bacterial pathogen Pseudomonas aeruginosa to cause both chronic and acute infections mainly relies on its capacity to finely modulate the expression of virulence factors through a complex network of regulatory circuits, including the pqs quorum sensing (QS) system. While in most Q...

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Detalles Bibliográficos
Autores principales: Baldelli, Valerio, D’Angelo, Francesca, Pavoncello, Viola, Fiscarelli, Ersilia Vita, Visca, Paolo, Rampioni, Giordano, Leoni, Livia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549961/
https://www.ncbi.nlm.nih.gov/pubmed/32423284
http://dx.doi.org/10.1080/21505594.2020.1770508

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