TMT-based quantitative proteomics analysis reveals the attenuated replication mechanism of Newcastle disease virus caused by nuclear localization signal mutation in viral matrix protein

Nuclear localization of cytoplasmic RNA virus proteins mediated by intrinsic nuclear localization signal (NLS) plays essential roles in successful virus replication. We previously reported that NLS mutation in the matrix (M) protein obviously attenuates the replication and pathogenicity of Newcastle...

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Detalles Bibliográficos
Autores principales: Duan, Zhiqiang, Yuan, Chao, Han, Yifan, Zhou, Lei, Zhao, Jiafu, Ruan, Yong, Chen, Jiaqi, Ni, Mengmeng, Ji, Xinqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549962/
https://www.ncbi.nlm.nih.gov/pubmed/32420802
http://dx.doi.org/10.1080/21505594.2020.1770482

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