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Low mortality of hospitalised patients with COVID-19 in a tertiary Danish hospital setting

OBJECTIVES: We aimed to describe clinical characteristics and outcomes of admitted COVID-19 patients in a Danish hospital setting where an early active government intervention was taken. METHODS: Prospective cohort study including all admitted patients to the COVID-19 unit at Odense University Hospi...

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Autores principales: Madsen, Lone Wulff, Lindvig, Susan Olaf, Rasmussen, Line Dahlerup, Knudtzen, Fredrikke Christie, Laursen, Christian B., Øvrehus, Anne, Nielsen, Stig Lønberg, Johansen, Isik Somuncu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550098/
https://www.ncbi.nlm.nih.gov/pubmed/33059095
http://dx.doi.org/10.1016/j.ijid.2020.10.018
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author Madsen, Lone Wulff
Lindvig, Susan Olaf
Rasmussen, Line Dahlerup
Knudtzen, Fredrikke Christie
Laursen, Christian B.
Øvrehus, Anne
Nielsen, Stig Lønberg
Johansen, Isik Somuncu
author_facet Madsen, Lone Wulff
Lindvig, Susan Olaf
Rasmussen, Line Dahlerup
Knudtzen, Fredrikke Christie
Laursen, Christian B.
Øvrehus, Anne
Nielsen, Stig Lønberg
Johansen, Isik Somuncu
author_sort Madsen, Lone Wulff
collection PubMed
description OBJECTIVES: We aimed to describe clinical characteristics and outcomes of admitted COVID-19 patients in a Danish hospital setting where an early active government intervention was taken. METHODS: Prospective cohort study including all admitted patients to the COVID-19 unit at Odense University Hospital from March 10 to April 21, 2020. Patients were assessed by a multidisciplinary team at admission. Outcome parameters were development of acute respiratory distress syndrome (ARDS), intensive care unit (ICU) admission, death and admission time. RESULTS: We included 83 patients (median age 62 years, 62.7% male). At hospitalization, 31.3% needed oxygen supplementation and the median National Early Warning Score was four. Median admission time was 7 days (Interquartile ranges (IQR) 3-12). In total, ARDS was diagnosed in 33.7% (28/83) of the patients corresponding to an incidence rate of 7.1 per 100 person days (95% CI: 4.1-10.2). Overall 13 patients (15.7%) were transferred to the ICU of whom 11 (84.6%) received corticosteroids.. No patients died while admitted to the ICU. Four patients (4.8%) died during admission. CONCLUSION: Despite similar patient characteristics compared to those reported by others, we found a low overall mortality of < 5%.
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spelling pubmed-75500982020-10-13 Low mortality of hospitalised patients with COVID-19 in a tertiary Danish hospital setting Madsen, Lone Wulff Lindvig, Susan Olaf Rasmussen, Line Dahlerup Knudtzen, Fredrikke Christie Laursen, Christian B. Øvrehus, Anne Nielsen, Stig Lønberg Johansen, Isik Somuncu Int J Infect Dis Article OBJECTIVES: We aimed to describe clinical characteristics and outcomes of admitted COVID-19 patients in a Danish hospital setting where an early active government intervention was taken. METHODS: Prospective cohort study including all admitted patients to the COVID-19 unit at Odense University Hospital from March 10 to April 21, 2020. Patients were assessed by a multidisciplinary team at admission. Outcome parameters were development of acute respiratory distress syndrome (ARDS), intensive care unit (ICU) admission, death and admission time. RESULTS: We included 83 patients (median age 62 years, 62.7% male). At hospitalization, 31.3% needed oxygen supplementation and the median National Early Warning Score was four. Median admission time was 7 days (Interquartile ranges (IQR) 3-12). In total, ARDS was diagnosed in 33.7% (28/83) of the patients corresponding to an incidence rate of 7.1 per 100 person days (95% CI: 4.1-10.2). Overall 13 patients (15.7%) were transferred to the ICU of whom 11 (84.6%) received corticosteroids.. No patients died while admitted to the ICU. Four patients (4.8%) died during admission. CONCLUSION: Despite similar patient characteristics compared to those reported by others, we found a low overall mortality of < 5%. The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2021-01 2020-10-12 /pmc/articles/PMC7550098/ /pubmed/33059095 http://dx.doi.org/10.1016/j.ijid.2020.10.018 Text en © 2020 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Madsen, Lone Wulff
Lindvig, Susan Olaf
Rasmussen, Line Dahlerup
Knudtzen, Fredrikke Christie
Laursen, Christian B.
Øvrehus, Anne
Nielsen, Stig Lønberg
Johansen, Isik Somuncu
Low mortality of hospitalised patients with COVID-19 in a tertiary Danish hospital setting
title Low mortality of hospitalised patients with COVID-19 in a tertiary Danish hospital setting
title_full Low mortality of hospitalised patients with COVID-19 in a tertiary Danish hospital setting
title_fullStr Low mortality of hospitalised patients with COVID-19 in a tertiary Danish hospital setting
title_full_unstemmed Low mortality of hospitalised patients with COVID-19 in a tertiary Danish hospital setting
title_short Low mortality of hospitalised patients with COVID-19 in a tertiary Danish hospital setting
title_sort low mortality of hospitalised patients with covid-19 in a tertiary danish hospital setting
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550098/
https://www.ncbi.nlm.nih.gov/pubmed/33059095
http://dx.doi.org/10.1016/j.ijid.2020.10.018
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