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Low mortality of hospitalised patients with COVID-19 in a tertiary Danish hospital setting
OBJECTIVES: We aimed to describe clinical characteristics and outcomes of admitted COVID-19 patients in a Danish hospital setting where an early active government intervention was taken. METHODS: Prospective cohort study including all admitted patients to the COVID-19 unit at Odense University Hospi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550098/ https://www.ncbi.nlm.nih.gov/pubmed/33059095 http://dx.doi.org/10.1016/j.ijid.2020.10.018 |
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author | Madsen, Lone Wulff Lindvig, Susan Olaf Rasmussen, Line Dahlerup Knudtzen, Fredrikke Christie Laursen, Christian B. Øvrehus, Anne Nielsen, Stig Lønberg Johansen, Isik Somuncu |
author_facet | Madsen, Lone Wulff Lindvig, Susan Olaf Rasmussen, Line Dahlerup Knudtzen, Fredrikke Christie Laursen, Christian B. Øvrehus, Anne Nielsen, Stig Lønberg Johansen, Isik Somuncu |
author_sort | Madsen, Lone Wulff |
collection | PubMed |
description | OBJECTIVES: We aimed to describe clinical characteristics and outcomes of admitted COVID-19 patients in a Danish hospital setting where an early active government intervention was taken. METHODS: Prospective cohort study including all admitted patients to the COVID-19 unit at Odense University Hospital from March 10 to April 21, 2020. Patients were assessed by a multidisciplinary team at admission. Outcome parameters were development of acute respiratory distress syndrome (ARDS), intensive care unit (ICU) admission, death and admission time. RESULTS: We included 83 patients (median age 62 years, 62.7% male). At hospitalization, 31.3% needed oxygen supplementation and the median National Early Warning Score was four. Median admission time was 7 days (Interquartile ranges (IQR) 3-12). In total, ARDS was diagnosed in 33.7% (28/83) of the patients corresponding to an incidence rate of 7.1 per 100 person days (95% CI: 4.1-10.2). Overall 13 patients (15.7%) were transferred to the ICU of whom 11 (84.6%) received corticosteroids.. No patients died while admitted to the ICU. Four patients (4.8%) died during admission. CONCLUSION: Despite similar patient characteristics compared to those reported by others, we found a low overall mortality of < 5%. |
format | Online Article Text |
id | pubmed-7550098 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. |
record_format | MEDLINE/PubMed |
spelling | pubmed-75500982020-10-13 Low mortality of hospitalised patients with COVID-19 in a tertiary Danish hospital setting Madsen, Lone Wulff Lindvig, Susan Olaf Rasmussen, Line Dahlerup Knudtzen, Fredrikke Christie Laursen, Christian B. Øvrehus, Anne Nielsen, Stig Lønberg Johansen, Isik Somuncu Int J Infect Dis Article OBJECTIVES: We aimed to describe clinical characteristics and outcomes of admitted COVID-19 patients in a Danish hospital setting where an early active government intervention was taken. METHODS: Prospective cohort study including all admitted patients to the COVID-19 unit at Odense University Hospital from March 10 to April 21, 2020. Patients were assessed by a multidisciplinary team at admission. Outcome parameters were development of acute respiratory distress syndrome (ARDS), intensive care unit (ICU) admission, death and admission time. RESULTS: We included 83 patients (median age 62 years, 62.7% male). At hospitalization, 31.3% needed oxygen supplementation and the median National Early Warning Score was four. Median admission time was 7 days (Interquartile ranges (IQR) 3-12). In total, ARDS was diagnosed in 33.7% (28/83) of the patients corresponding to an incidence rate of 7.1 per 100 person days (95% CI: 4.1-10.2). Overall 13 patients (15.7%) were transferred to the ICU of whom 11 (84.6%) received corticosteroids.. No patients died while admitted to the ICU. Four patients (4.8%) died during admission. CONCLUSION: Despite similar patient characteristics compared to those reported by others, we found a low overall mortality of < 5%. The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2021-01 2020-10-12 /pmc/articles/PMC7550098/ /pubmed/33059095 http://dx.doi.org/10.1016/j.ijid.2020.10.018 Text en © 2020 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Madsen, Lone Wulff Lindvig, Susan Olaf Rasmussen, Line Dahlerup Knudtzen, Fredrikke Christie Laursen, Christian B. Øvrehus, Anne Nielsen, Stig Lønberg Johansen, Isik Somuncu Low mortality of hospitalised patients with COVID-19 in a tertiary Danish hospital setting |
title | Low mortality of hospitalised patients with COVID-19 in a tertiary Danish hospital setting |
title_full | Low mortality of hospitalised patients with COVID-19 in a tertiary Danish hospital setting |
title_fullStr | Low mortality of hospitalised patients with COVID-19 in a tertiary Danish hospital setting |
title_full_unstemmed | Low mortality of hospitalised patients with COVID-19 in a tertiary Danish hospital setting |
title_short | Low mortality of hospitalised patients with COVID-19 in a tertiary Danish hospital setting |
title_sort | low mortality of hospitalised patients with covid-19 in a tertiary danish hospital setting |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550098/ https://www.ncbi.nlm.nih.gov/pubmed/33059095 http://dx.doi.org/10.1016/j.ijid.2020.10.018 |
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