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Multiple Simultaneous Mature Teratomas of the Spinal Cord in an Adult

Teratomas of the spinal cord are rare tumors, particularly in adults, but there is an increasing body of literature documenting both their diagnosis and successful treatment with surgical resection. However, to date, the literature has largely characterized spinal teratomas as single solitary lesion...

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Autores principales: DeWitt, Michelle, Richardson, Timothy E, Reddy, Gaddum D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550225/
https://www.ncbi.nlm.nih.gov/pubmed/33062526
http://dx.doi.org/10.7759/cureus.10409
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author DeWitt, Michelle
Richardson, Timothy E
Reddy, Gaddum D
author_facet DeWitt, Michelle
Richardson, Timothy E
Reddy, Gaddum D
author_sort DeWitt, Michelle
collection PubMed
description Teratomas of the spinal cord are rare tumors, particularly in adults, but there is an increasing body of literature documenting both their diagnosis and successful treatment with surgical resection. However, to date, the literature has largely characterized spinal teratomas as single solitary lesions. Here, we report on an adult patient who presented with signs of progressive lower extremity weakness. Imaging demonstrated two simultaneous lesions of the spine, an extramedullary lesion in the upper thoracic region and an intramedullary lesion in the mid-thoracic region. Both lesions were resected and pathologically determined to be mature spinal teratomas. To our knowledge, this is only the second report of this tumor presenting simultaneously at more than one location in the spine and the first time it has presented both as an intra-axial and extra-axial lesion. Our results suggest that the presence of more than one simultaneous lesion does not necessarily increase the risk of a more aggressive immature pathology. 
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spelling pubmed-75502252020-10-13 Multiple Simultaneous Mature Teratomas of the Spinal Cord in an Adult DeWitt, Michelle Richardson, Timothy E Reddy, Gaddum D Cureus Neurosurgery Teratomas of the spinal cord are rare tumors, particularly in adults, but there is an increasing body of literature documenting both their diagnosis and successful treatment with surgical resection. However, to date, the literature has largely characterized spinal teratomas as single solitary lesions. Here, we report on an adult patient who presented with signs of progressive lower extremity weakness. Imaging demonstrated two simultaneous lesions of the spine, an extramedullary lesion in the upper thoracic region and an intramedullary lesion in the mid-thoracic region. Both lesions were resected and pathologically determined to be mature spinal teratomas. To our knowledge, this is only the second report of this tumor presenting simultaneously at more than one location in the spine and the first time it has presented both as an intra-axial and extra-axial lesion. Our results suggest that the presence of more than one simultaneous lesion does not necessarily increase the risk of a more aggressive immature pathology.  Cureus 2020-09-12 /pmc/articles/PMC7550225/ /pubmed/33062526 http://dx.doi.org/10.7759/cureus.10409 Text en Copyright © 2020, DeWitt et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurosurgery
DeWitt, Michelle
Richardson, Timothy E
Reddy, Gaddum D
Multiple Simultaneous Mature Teratomas of the Spinal Cord in an Adult
title Multiple Simultaneous Mature Teratomas of the Spinal Cord in an Adult
title_full Multiple Simultaneous Mature Teratomas of the Spinal Cord in an Adult
title_fullStr Multiple Simultaneous Mature Teratomas of the Spinal Cord in an Adult
title_full_unstemmed Multiple Simultaneous Mature Teratomas of the Spinal Cord in an Adult
title_short Multiple Simultaneous Mature Teratomas of the Spinal Cord in an Adult
title_sort multiple simultaneous mature teratomas of the spinal cord in an adult
topic Neurosurgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550225/
https://www.ncbi.nlm.nih.gov/pubmed/33062526
http://dx.doi.org/10.7759/cureus.10409
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