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Chimeric Virus-Like Particles and Capsomeres Induce Similar CD8(+) T Cell Responses but Differ in Capacity to Induce CD4(+) T Cell Responses and Antibody Responses

Despite extensive research, the development of an effective malaria vaccine remains elusive. The induction of robust and sustained T cell and antibody response by vaccination is an urgent unmet need. Chimeric virus-like particles (VLPs) are a promising vaccine platform. VLPs are composed of multiple...

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Detalles Bibliográficos
Autores principales:	Pattinson, David J., Apte, Simon H., Wibowo, Nani, Rivera-Hernandez, Tania, Groves, Penny L., Middelberg, Anton P. J., Doolan, Denise L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550421/ https://www.ncbi.nlm.nih.gov/pubmed/33133076 http://dx.doi.org/10.3389/fimmu.2020.564627

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