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The Polyphenol Pterostilbene Ameliorates the Myopathic Phenotype of Collagen VI Deficient Mice via Autophagy Induction

The induction of autophagy, the catabolic pathway by which damaged or unnecessary cellular components are subjected to lysosome-mediated degradation and recycling, is impaired in Collagen VI (COL6) null mice and COL6-related myopathies. This autophagic impairment causes an accumulation of dysfunctio...

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Detalles Bibliográficos
Autores principales: Metti, Samuele, Gambarotto, Lisa, Chrisam, Martina, Spina, Martina La, Baraldo, Martina, Braghetta, Paola, Blaauw, Bert, Bonaldo, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550465/
https://www.ncbi.nlm.nih.gov/pubmed/33134297
http://dx.doi.org/10.3389/fcell.2020.580933