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The Polyphenol Pterostilbene Ameliorates the Myopathic Phenotype of Collagen VI Deficient Mice via Autophagy Induction
The induction of autophagy, the catabolic pathway by which damaged or unnecessary cellular components are subjected to lysosome-mediated degradation and recycling, is impaired in Collagen VI (COL6) null mice and COL6-related myopathies. This autophagic impairment causes an accumulation of dysfunctio...
Autores principales: | Metti, Samuele, Gambarotto, Lisa, Chrisam, Martina, Spina, Martina La, Baraldo, Martina, Braghetta, Paola, Blaauw, Bert, Bonaldo, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550465/ https://www.ncbi.nlm.nih.gov/pubmed/33134297 http://dx.doi.org/10.3389/fcell.2020.580933 |
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