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Active immunotherapy and alternative therapeutic modalities for Alzheimer's disease

As knowledge of Alzheimer's disease (AD) progression improves, the field has recognized the need to diversify the pipeline, broaden strategies and approaches to therapies, as well as delivery mechanisms. A better understanding of the earliest biological processes of AD/dementia would help infor...

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Autores principales: Weninger, Stacie, Sperling, Bjorn, Alexander, Robert, Ivarsson, Magnus, Menzies, Fiona M., Powchik, Peter, Weber, Christopher J., Altar, C. Anthony, Crystal, Ronald G., Haggarty, Stephen J., Loring, Jeanne, Bain, Lisa J., Carrillo, Maria C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550557/
https://www.ncbi.nlm.nih.gov/pubmed/33083513
http://dx.doi.org/10.1002/trc2.12090
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author Weninger, Stacie
Sperling, Bjorn
Alexander, Robert
Ivarsson, Magnus
Menzies, Fiona M.
Powchik, Peter
Weber, Christopher J.
Altar, C. Anthony
Crystal, Ronald G.
Haggarty, Stephen J.
Loring, Jeanne
Bain, Lisa J.
Carrillo, Maria C.
author_facet Weninger, Stacie
Sperling, Bjorn
Alexander, Robert
Ivarsson, Magnus
Menzies, Fiona M.
Powchik, Peter
Weber, Christopher J.
Altar, C. Anthony
Crystal, Ronald G.
Haggarty, Stephen J.
Loring, Jeanne
Bain, Lisa J.
Carrillo, Maria C.
author_sort Weninger, Stacie
collection PubMed
description As knowledge of Alzheimer's disease (AD) progression improves, the field has recognized the need to diversify the pipeline, broaden strategies and approaches to therapies, as well as delivery mechanisms. A better understanding of the earliest biological processes of AD/dementia would help inform drug target selection. Currently there are a number of programs exploring these alternate avenues. This meeting will allow experts in the field (academia, industry, government) to provide perspectives and experiences that can help elucidate what the pipeline looks like today and what avenues hold promise in developing new therapies across the stages of AD. The focus here is on Active Immunotherapies and Alternative Therapeutic Modalities. This topic includes active vaccines, antisense oligomers, and cell‐based therapy among others, and highlights new clinical developments that utilize these modalities.
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spelling pubmed-75505572020-10-19 Active immunotherapy and alternative therapeutic modalities for Alzheimer's disease Weninger, Stacie Sperling, Bjorn Alexander, Robert Ivarsson, Magnus Menzies, Fiona M. Powchik, Peter Weber, Christopher J. Altar, C. Anthony Crystal, Ronald G. Haggarty, Stephen J. Loring, Jeanne Bain, Lisa J. Carrillo, Maria C. Alzheimers Dement (N Y) Perspectives As knowledge of Alzheimer's disease (AD) progression improves, the field has recognized the need to diversify the pipeline, broaden strategies and approaches to therapies, as well as delivery mechanisms. A better understanding of the earliest biological processes of AD/dementia would help inform drug target selection. Currently there are a number of programs exploring these alternate avenues. This meeting will allow experts in the field (academia, industry, government) to provide perspectives and experiences that can help elucidate what the pipeline looks like today and what avenues hold promise in developing new therapies across the stages of AD. The focus here is on Active Immunotherapies and Alternative Therapeutic Modalities. This topic includes active vaccines, antisense oligomers, and cell‐based therapy among others, and highlights new clinical developments that utilize these modalities. John Wiley and Sons Inc. 2020-10-12 /pmc/articles/PMC7550557/ /pubmed/33083513 http://dx.doi.org/10.1002/trc2.12090 Text en © 2020 The Authors. Alzheimer's & Dementia: Translational Research & Clinical Interventions published by Wiley Periodicals, Inc. on behalf of Alzheimer's Association. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Perspectives
Weninger, Stacie
Sperling, Bjorn
Alexander, Robert
Ivarsson, Magnus
Menzies, Fiona M.
Powchik, Peter
Weber, Christopher J.
Altar, C. Anthony
Crystal, Ronald G.
Haggarty, Stephen J.
Loring, Jeanne
Bain, Lisa J.
Carrillo, Maria C.
Active immunotherapy and alternative therapeutic modalities for Alzheimer's disease
title Active immunotherapy and alternative therapeutic modalities for Alzheimer's disease
title_full Active immunotherapy and alternative therapeutic modalities for Alzheimer's disease
title_fullStr Active immunotherapy and alternative therapeutic modalities for Alzheimer's disease
title_full_unstemmed Active immunotherapy and alternative therapeutic modalities for Alzheimer's disease
title_short Active immunotherapy and alternative therapeutic modalities for Alzheimer's disease
title_sort active immunotherapy and alternative therapeutic modalities for alzheimer's disease
topic Perspectives
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550557/
https://www.ncbi.nlm.nih.gov/pubmed/33083513
http://dx.doi.org/10.1002/trc2.12090
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