Celecoxib Exerts Neuroprotective Effects in β-Amyloid-Treated SH-SY5Y Cells Through the Regulation of Heme Oxygenase-1: Novel Insights for an Old Drug

The formation and aggregation of amyloid-β-peptide (Aβ) into soluble and insoluble species represent the pathological hallmarks of Alzheimer’s disease (AD). Over the last few years, however, soluble Aβ (sAβ) prevailed over fibrillar Aβ (fAβ) as determinant of neurotoxicity. One of the main therapeut...

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Detalles Bibliográficos
Autores principales: Mhillaj, Emanuela, Papi, Massimiliano, Paciello, Fabiola, Silvestrini, Andrea, Rolesi, Rolando, Palmieri, Valentina, Perini, Giordano, Fetoni, Anna Rita, Trabace, Luigia, Mancuso, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550645/
https://www.ncbi.nlm.nih.gov/pubmed/33134292
http://dx.doi.org/10.3389/fcell.2020.561179

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