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XMAP215 and γ-tubulin additively promote microtubule nucleation in purified solutions
Microtubule nucleation is spatiotemporally regulated in cells by several known molecules, including the template γ-tubulin and the polymerase XMAP215. The role of XMAP215 in nucleation is under debate, specifically whether it acts independently as a polymerase or acts dependently with γ-tubulin. We...
Autores principales: | King, Brianna R., Moritz, Michelle, Kim, Haein, Agard, David A., Asbury, Charles L., Davis, Trisha N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550701/ https://www.ncbi.nlm.nih.gov/pubmed/32726183 http://dx.doi.org/10.1091/mbc.E20-02-0160 |
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