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Transgenic Chlamydomonas Expressing Human Transient Receptor Potential Ankyrin 1 (TRPA1) Channels to Assess the Effect of Agonists and Antagonists

Transient receptor potential ankyrin 1 (TRPA1) channel is an ion channel whose gating is controlled by agonists, such as allyl isothiocyanate (AITC), and temperature. Since TRPA1 is associated with various disease symptoms and chemotherapeutic side effects, it is a frequent target of drug developmen...

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Detalles Bibliográficos
Autores principales: Yoshida, Megumi, Yamamiya, Ryodai, Shimizu, Yuto, Yoshimura, Kenjiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550780/
https://www.ncbi.nlm.nih.gov/pubmed/33117171
http://dx.doi.org/10.3389/fphar.2020.578955