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The Unfolded Protein Response and Autophagy as Drug Targets in Neuropsychiatric Disorders

Neurons are polarized in structure with a cytoplasmic compartment extending into dendrites and a long axon that terminates at the synapse. The high level of compartmentalization imposes specific challenges for protein quality control in neurons making them vulnerable to disturbances that may lead to...

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Detalles Bibliográficos
Autores principales: Srinivasan, Vignesh, Korhonen, Laura, Lindholm, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550790/
https://www.ncbi.nlm.nih.gov/pubmed/33132844
http://dx.doi.org/10.3389/fncel.2020.554548