Ticagrelor-Related Severe Dyspnoea: Mechanisms, Characteristic Features, Differential Diagnosis and Treatment

With a growing number of patients on ticagrelor therapy after stent implantation, we observe many cases of side effects of the drug, mostly dyspnoea and bradycardia. In our article we present 2 patients, in which the symptoms were particularly severe. Then we describe possible mechanisms of these co...

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Detalles Bibliográficos
Autores principales: Krakowiak, Alicja, Kuleta, Jakub, Plech, Iwona, Zarębiński, Maciej, Wojciechowska, Małgorzata, Wretowski, Dominik, Cudnoch-Jędrzejewska, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550933/
https://www.ncbi.nlm.nih.gov/pubmed/33100831
http://dx.doi.org/10.1177/1179547620956634
Descripción
Sumario:With a growing number of patients on ticagrelor therapy after stent implantation, we observe many cases of side effects of the drug, mostly dyspnoea and bradycardia. In our article we present 2 patients, in which the symptoms were particularly severe. Then we describe possible mechanisms of these complications, explain how to carry out differential diagnosis, discuss when to switch ticagrelor to other antiplatelet drug and finally we present the way to deal with the symptoms.

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