Ticagrelor-Related Severe Dyspnoea: Mechanisms, Characteristic Features, Differential Diagnosis and Treatment

With a growing number of patients on ticagrelor therapy after stent implantation, we observe many cases of side effects of the drug, mostly dyspnoea and bradycardia. In our article we present 2 patients, in which the symptoms were particularly severe. Then we describe possible mechanisms of these co...

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Autores principales: Krakowiak, Alicja, Kuleta, Jakub, Plech, Iwona, Zarębiński, Maciej, Wojciechowska, Małgorzata, Wretowski, Dominik, Cudnoch-Jędrzejewska, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550933/
https://www.ncbi.nlm.nih.gov/pubmed/33100831
http://dx.doi.org/10.1177/1179547620956634
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author Krakowiak, Alicja
Kuleta, Jakub
Plech, Iwona
Zarębiński, Maciej
Wojciechowska, Małgorzata
Wretowski, Dominik
Cudnoch-Jędrzejewska, Agnieszka
author_facet Krakowiak, Alicja
Kuleta, Jakub
Plech, Iwona
Zarębiński, Maciej
Wojciechowska, Małgorzata
Wretowski, Dominik
Cudnoch-Jędrzejewska, Agnieszka
author_sort Krakowiak, Alicja
collection PubMed
description With a growing number of patients on ticagrelor therapy after stent implantation, we observe many cases of side effects of the drug, mostly dyspnoea and bradycardia. In our article we present 2 patients, in which the symptoms were particularly severe. Then we describe possible mechanisms of these complications, explain how to carry out differential diagnosis, discuss when to switch ticagrelor to other antiplatelet drug and finally we present the way to deal with the symptoms.
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spelling pubmed-75509332020-10-23 Ticagrelor-Related Severe Dyspnoea: Mechanisms, Characteristic Features, Differential Diagnosis and Treatment Krakowiak, Alicja Kuleta, Jakub Plech, Iwona Zarębiński, Maciej Wojciechowska, Małgorzata Wretowski, Dominik Cudnoch-Jędrzejewska, Agnieszka Clin Med Insights Case Rep Case Report With a growing number of patients on ticagrelor therapy after stent implantation, we observe many cases of side effects of the drug, mostly dyspnoea and bradycardia. In our article we present 2 patients, in which the symptoms were particularly severe. Then we describe possible mechanisms of these complications, explain how to carry out differential diagnosis, discuss when to switch ticagrelor to other antiplatelet drug and finally we present the way to deal with the symptoms. SAGE Publications 2020-10-08 /pmc/articles/PMC7550933/ /pubmed/33100831 http://dx.doi.org/10.1177/1179547620956634 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Krakowiak, Alicja
Kuleta, Jakub
Plech, Iwona
Zarębiński, Maciej
Wojciechowska, Małgorzata
Wretowski, Dominik
Cudnoch-Jędrzejewska, Agnieszka
Ticagrelor-Related Severe Dyspnoea: Mechanisms, Characteristic Features, Differential Diagnosis and Treatment
title Ticagrelor-Related Severe Dyspnoea: Mechanisms, Characteristic Features, Differential Diagnosis and Treatment
title_full Ticagrelor-Related Severe Dyspnoea: Mechanisms, Characteristic Features, Differential Diagnosis and Treatment
title_fullStr Ticagrelor-Related Severe Dyspnoea: Mechanisms, Characteristic Features, Differential Diagnosis and Treatment
title_full_unstemmed Ticagrelor-Related Severe Dyspnoea: Mechanisms, Characteristic Features, Differential Diagnosis and Treatment
title_short Ticagrelor-Related Severe Dyspnoea: Mechanisms, Characteristic Features, Differential Diagnosis and Treatment
title_sort ticagrelor-related severe dyspnoea: mechanisms, characteristic features, differential diagnosis and treatment
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550933/
https://www.ncbi.nlm.nih.gov/pubmed/33100831
http://dx.doi.org/10.1177/1179547620956634
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